Example sentences for: nnbc
How can you use “nnbc” in a sentence? Here are some example sentences to help you improve your vocabulary:
As in the present investigation, Roux-Dosseto et al . [ 26 ] found that c- myc amplification among NNBC patients was significantly associated with earlier recurrence in univariate and multivariate analyses.
General details for the double differential PCR technique, reproducibility and clinical significance were described previously [ 17 18 28 40 ] . A cutoff point of more than 2.0 average gene copy number (AGCN) was considered to be positive for HER-2 / neu amplification [ 40 ] . To calculate the cutoff point for c- myc amplification, all NNBC patients were subjected to Classification and Regression Trees (CART) analysis.
plasminogen activator inhibitor-1), after further randomized studies have been conducted, to confirm whether NNBC patients should receive adjuvant systemic therapy [ 47 48 49 ] .
Although deregulated HER-2 / neu activity can strongly stimulate cytoplasmic signalling pathways, which in turn impinge on c- myc at multiple levels causing its deregulated expression [ 46 ] , this scenario does not appear to be active in NNBC because the recurrence rate of 22 c- myc and HER-2 / neu coamplified patients was only 9%.
AGCN = average gene copy number; CART = Classification and Regression Trees; CMF = cyclophosphamide, methotrexate, 5-fluorouracil; DFS = disease-free survival; NNBC = node-negative breast cancer; FEC = fluorouracil, epirubicin, cyclophosphamide; OS = overall survival; PCR = poly-merase chain reaction.