Example sentences for: nfκb

How can you use “nfκb” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The human alveolar epithelial cell line A549 and normal human bronchial epithelial cells (NHBEs) were exposed to the particulate fraction of cigarette smoke (cigarette smoke condensate; CSC) and examined for the production of proinflammatory cytokines and activation of MAPK and NFκB.

  • A number of chemokines and cytokines that are regulated by NFκB1 were also induced (Figure 7), including IL-6, Gro-1, Gro-2, and a number of small inducible cytokine family members (SCY).

  • The 50 most highly induced named genes are shown in Figure 3. Twenty percent of these genes are either involved in NFκB signal transduction or directly activated by NFκB.

  • NFκB is a ubiquitous transcription factor involved in regulating inflammatory responses, and its targets include several of the genes encoding cytokines and chemokines.

  • To determine whether upregulation of cytokine production by CSC involved activation of NFκB, we examined CSC-treated epithelial cells for phosphorylation of the inhibitor of NFκB (IκB).


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