Words similar to nfκb

Example sentences for: nfκb

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In essence, these results demonstrate that NHBEs respond to moderate doses of CSC by activating both the ERK1/2 and the NFκB pathways, and by upregulating the expression of several genes encoding proinflammatory molecules.
A number of chemokines and cytokines that are regulated by NFκB1 were also induced (Figure 7), including IL-6, Gro-1, Gro-2, and a number of small inducible cytokine family members (SCY).
Of the 50 named genes most highly induced in all infections, 40% are either involved in NFκB signaling, or are responsive to NFκB activation.
We chose to look at Gro-1 (MSGA) production and secretion as it appeared to be one of the most highly induced chemokines at the RNA level (Figures 2, 6), and is known to be a target of NFκB activation [ 47].
Other cell types may be able to better distinguish between pathogenic and nonpathogenic L. monocytogenes ; for example, expression of the virulence factor LLO, the hemolysin responsible in part for invasion of L. monocytogenes into the host cell cytoplasm, is necessary for L. monocytogenes to activate neutrophils [ 34], stimulate prolonged TNFα production by macrophages [ 36, 37], and induce NFκB nuclear translocation and cytokine secretion by HUVEC human vascular endothelial cells [ 35, 39].