Example sentences for: nfκb

How can you use “nfκb” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The results of our studies demonstrate that the mechanism underlying these acute inflammatory events involves activation of specific signaling pathways such as MAPK (ERK1/2) and NFκB, leading to the release of proinflammatory cytokines.

  • The human alveolar epithelial cell line A549 and normal human bronchial epithelial cells (NHBEs) were exposed to the particulate fraction of cigarette smoke (cigarette smoke condensate; CSC) and examined for the production of proinflammatory cytokines and activation of MAPK and NFκB.

  • Among the most highly induced were the genes encoding NFκB1, RelB, IκB-alpha (the inhibitor of NFκB1), IκKε (IκB kinase-epsilon), and NFκB-inducing kinase or Map-3-kinase-14 (NIK, MAP3K14).

  • The CSC-induced increase in IL-1β expression was also reduced by treatment of the cells with PD98059 or the NFκB inhibitor, PDTC (Fig.

  • Activation of NFκB involves the increased phosphorylation and proteolytic degradation of IκB.


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