Example sentences for: nfat

How can you use “nfat” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • p(NFAT)

  • However, studies of the relationships between the proteins of calcium metabolism and calcium-regulated signaling pathways—as described here in a simplified manner with respect to TRPC3, calcineurin, and NFAT proteins—are illustrative of progress in this field.

  • The transactivation properties of the two proteins were tested by in vitro transcription using the reconstituted transcription system and a DNA template consisting of three high affinity NFAT sites upstream of the adenovirus major late core promoter and a 200 bp G-less cassette.

  • Other notable findings point to additional signaling proteins (CAMK, p38MAPK, and AMPK) and transcription factors (PGC-1, MEF2, ATF2, PPARs) active in pathways that intersect with calcineurin–NFAT signaling [31,43,44,45,46,47,48] (see Figure 2).

  • Upon receipt of the appropriate calcium signal, calcineurin is activated and removes phosphate groups from NFAT, thereby permitting translocation of NFAT to the nucleus.


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