Words similar to nfat

Example sentences for: nfat

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The transcriptional effects of individual NFAT family members, including NFATp, NFATc, NFAT3, NFAT4/x, and NFAT5, are beginning to emerge.
For example, even though the NFAT sites in the DNA template used in the transcription experiments in Figures 3Aand 3Bwere high affinity NFAT binding sites that were not part of a composite element, it remained possible that AP-1 proteins in the nuclear extract contributed to the activation observed.
Once in the nucleus, NFAT can bind DNA elements in target promoters, often in association with other resident and co-induced nuclear proteins [ 1].
3 -MLP-G-less consists of three direct copies of the murine IL-4 high affinity NFAT site (region -82 to -64 of the murine IL-4 promoter) upstream of an adenovirus major late core promoter (-53 to +10) and a 200 bp G-less cassette.
Upon receipt of the appropriate calcium signal, calcineurin is activated and removes phosphate groups from NFAT, thereby permitting translocation of NFAT to the nucleus.