Words similar to nelf
Example sentences for: nelf
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Antisense depletion of NELF led to a decrease in both olfactory axonal outgrowth and the number of GnRH neurons exiting the epithelium.
In fact, Kramer and Wray [ 42 ] have identified a novel gene, nasal embryonic LHRH (GnRH) factor or NELF, which is expressed by GnRH neurons during their migratory phase and olfactory sensory neurons as they initiate axonogenesis.
It consists minimally of 5,6- dichloro-1-β-D-ribofuranosylbenzimidazole riboside (DRB)- sensitivity-inducing factor (DSIF) [4] and negative elongation factor (NELF) [5].
These modifications result in heavily phosphorylated RNAPII (RNAPIIo), the recruitment of the Elongator, which contains splicing and polyadenylation machineries, and the conversions of DSIF and NELF into elongation factors.
When recruited to stalled transcription complexes, P-TEFb phosphorylates serines at position 2 in the CTD [8], the Spt5 subunit of DSIF [9], and the RD subunit of NELF [10].