Example sentences for: nedd

How can you use “nedd” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • NEDD1 -UF 5'-TGGATATTTTTTAGTTTAGTGTG-3'

  • While Csn5 is thought to impede the action of ubiquitin ligases through shaving cullins from their Rub1/Nedd8 modification (and possibly also by deubiquitinating substrates bound to the cullins), the outcome of Rpn11 inhibition will depend largely on whether Rpn11 participates primarily in shaving substrates from their chains, promoting release and rescue, or in trimming the polyubiquitin tag, allowing for proteolysis quality control (Figure 2).

  • In particular, one subunit—Csn5—moderates SCF (Skp1–cullin–F box) and other cullin-based E3 ubiquitin ligases by removal of the ubiquitin-like Rub1/Nedd8 molecule from the cullin subunit of the ligase complex.

  • NEDD8 modification stimulates SCF-dependent substrate ubiquitylation in vitro [ 2, 3, 4], and mutant CUL1 resistant to NEDD8 modification is defective in vivo [ 5].

  • NEDD1 -UR 5'-CAACCCCCTATTATATTACTACA-3'


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