Words similar to necrosis
Example sentences for: necrosis
How can you use “necrosis” in a sentence? Here are some example sentences to help you improve your vocabulary:
For instance, tumor necrosis factor-α (TNF-α) can modify intracellular signal transduction and regulate ionic channel activities in various epithelial cells [ 9 ] . A few studies have shown that cytokines can alter biliary epithelial cell function [ 10 11 ] .
Immunoblotting analysis showed distinct cleavage fragments of Golgi autoantigens generated during apoptosis and necrosis.
[ 30 ] demonstrated host caspases-8 and -3 to play a role in S. aureus -induced apoptosis, and caspase-8 is known to be associated with apoptosis triggered by engagement of death receptors [ 35 ] . Several recent studies have associated microbial induction of apoptosis with the production of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).
BSA = Bovine serum albumin; CSC = cigarette smoke condensate; ERK = extracellular signal-regulated kinase; GM-CSF = granulocyte-macrophage colony-stimulating factor; HBE = human bronchial epithelial cell; IL = interleukin; IκB = inhibitor of NFκB; MAPK = mitogen-activated protein kinase; MEK-1 = MAPK kinase; NFκB = nuclear factor-kappa B; NHBE = normal human bronchial epithelial cell; PBS = phosphate-buffered saline; PDTC = pyrrolidine dithiocarbamate; RT-PCR = reverse transcriptase-polymerase chain reaction; sICAM = soluble intercellular adhesion molecule; TNF = tumour necrosis factor; TUNEL = deoxynucleotidyl transferase-mediated dUTP nick end labeling
In agreement with previous studies, the Tie1 receptor was detected on vascular endothelial cells [ 4 25 ] and recently on synovial lining cells [ 26 ] . It has been shown that tumor necrosis factor-α and VEGF activate membrane-associated metalloproteinases that release soluble Tie1 from the cell surface of endothelial cells and thereby decrease membrane-bound Tie1 expression [ 27 ] . The upregulation of Tie1 mRNA and protein expression in RA is not consistent with these findings and this may be due to the fact that the inflammatory milieu in RA synovial tissue is far more complex than the in vitro system.
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