Example sentences for: necrosis

How can you use “necrosis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Analysis of post-translational modifications in intracellular autoantigens associated with apoptosis and necrosis should provide important insights into the possible role of cell death in the generation of potentially autoantigenic forms of cellular antigens.

  • BAL = bronchoalveolar lavage; BSA = bovine serum albumin; C/EBP = CCAAT/enhancer binding protein; COX-2 = cyclooxygenase-2; CREB = cAMP response element binding protein; FBS = fetal bovine serum; fMLP = n-formyl-methionyl-leucyl-phenylalanine; HBSS = Hank's balanced salt solution; ICAM-1 = intercellular adhesion molecule-1; LPS = lipoplysaccharide; MAP = mitogen activated protein; MIP-2 = macrophage inflammatory protein-2; NF-κB = nuclear factor-kappa B; PBS = phosphate-buffered saline; PI3K = phosphatidyl inositol 3 kinase; PKB = protein kinase B; RT-PCR = Reverse transcription-polymerase chain reaction; TBE = Tris borate EDTA; TNF-α = tumor necrosis factor alpha

  • No Golgi staining was observed in HEp-2 cells treated with 10 μM STS for 24 hours or with 0.1% H 2 O 2 (data not shown), presumably due to the extensive cytoplasmic damage associated with necrosis.

  • LPS is a major component of the cell wall of gram-negative bacteria and is known to trigger a variety of inflammatory reactions in macrophages and other cells having CD14 receptors [ 7 8 ] . In particular, LPS is known to stimulate the macrophage secretion of nitric oxide [ 9 ] and inflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1-beta (IL-1-beta) [ 10 ] . For this reason, we also determined if TNF-alpha or IL-1-beta were capable of enhancing the cytotoxic effects of CEES.

  • 5°C) may represent tissue necrosis.


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