Words similar to ncoa

Example sentences for: ncoa

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The NcoA family members constitute SRC-1/NcoA-1 [ 89 ] , TIF2/GRIP1/NcoA-2, [ 94 95 ] and pCIP/ACTR/AIB1 [ 96 97 98 ] proteins, which interact with liganded RA receptor (RAR), and CBP/p300.
Compared to LNCaP cells, normal male genital fibroblasts show distinctly lower baseline expression of several AR co-regulators (such as NCOA2 (GRIP-1), NCOA3 (TRAM-1), ARA54 (RNF14), data not shown).
Upon binding of the hormone, these corepressors dissociate from the DNA-bound receptor, which subsequently recruits a nuclear receptor coactivator (NCoA) complex.
Overexpression of these NCoA factors enhances ligand-induced transactivation of several nuclear receptors [ 99 ] . A weak intrinsic HAT activity has been reported in SRC-1/NCoA-1 and pCIP/ACTR/AIB1, suggesting that chromatin remodeling may also be a function of these NCoA factors [ 99 100 ] ; although they do not appear to contain regions homologous to the HAT domains of CBP/p300 or p/CAF.