Example sentences for: nad

How can you use “nad” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The weight loss for NAD was again different from Obesity III patients who were AD or ADSx, but AD and ADSx were not significantly different (Fisher, NAD-AD: p < 0.001, NAD-ADSx: p < 0.01, AD-ADSx: p < 0.657).

  • NAD, all-trans retinal, all-trans retinoic acid, dimethylsulfoxide, mammalian protease inhibitor cocktail, nitroblue tetrazolium, and pyrazole were obtained from Sigma Chemical Co., St. Louis, MO.

  • Subtree-neighbors can be useful if there is (partial) agreement among their annotations (for example: if the subtree-neighbors of a query are NAD +-dependent isocitrate dehydrogenase and NADP +-dependent isocitrate dehydrogenase we can suppose that the query is likely to be a isocitrate dehydrogenase, but it is not possible to determine whether it is dependent on NAD +or NADP +).

  • Organic phosphate compounds are the central metabolites of all biological systems [ 1 2 ] . Some are the basic building blocks of nucleic acids, some like ATP and GTP, are additionally, cellular energy stores, others like cAMP or cGMP are messengers in signal transduction, and, yet others, such as FAD, NAD, thiamine phosphates and pyridoxal phosphate are cofactors for a range of enzymes [ 1 2 ] . Protein domains belonging to a relatively small set of structural folds are known to bind or catalyze reactions that utilize these organic phosphate compounds (see SCOP database: http://scop.mrc-lmb.cam.ac.uk/scop/) [ 3 4 ] . Several of these folds trace back to some of the earliest phases of the evolution of the protein world, and participate in a wide range of disparate biological functions in extant proteins [ 4 5 ] . Some folds, such as the P-loop fold, the Rossmann fold and the Hsp70-like fold, have been well studied, and comprise mainly of dedicated nucleotide binding or hydrolyzing proteins [ 6 7 8 9 ] . Others, such as the palm-domain, which is found in adenylyl cyclases and various nucleic acid polymerases, belong to more generalized protein folds that contain representatives with diverse biochemical activities [ 4 10 11 ] . Current availability of extensive genome sequence data, allows one to identify less numerous, nevertheless biological important organic phosphate-binding domains that may have previous eluded detection.

  • ADSx was no more successful than AD, but had fewer visits, comparable to NAD, in this respect, ADSx showing characteristics intermediate between AD and NAD.


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