Words similar to nadir

Example sentences for: nadir

How can you use “nadir” in a sentence? Here are some example sentences to help you improve your vocabulary:

They knew that the RJR Nabisco-leveraged buyout represented the nadir of that era's financial engineering.
3. Periprocedural MI events (occurring during or <24 hours after percutaneous coronary intervention): CK-MB ≥ 3 × ULN and >50% above the prior nadir value.
In the latter category, the practice probably reached its nadir with headshrinking.
Filgrastim (recombinant methionyl human granulocyte colony-stimulating factor) has been shown to reduce the depth of the nadir ANC, shorten the duration of neutropenia, and reduce the risk of febrile neutropenia [ 3 ] , thereby maintaining chemotherapy dose [ 4 5 ] . Many patients with early-stage breast cancer do not receive the full chemotherapy dose intensity recommended in conventional adjuvant chemotherapy regimens [ 6 7 8 ] . Neutropenia is the primary reason for chemotherapy dose delays and reductions [ 1 6 7 ] .
Model-derived point estimates for the probability of subsequent neutropenic events as a function of first-cycle nadir ANC and an average first-cycle decrease in hemoglobin concentration are presented in Fig.