Example sentences for: muscimol

How can you use “muscimol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Furthermore, muscimol inhibited dye-transfer between neurons in the SCN culture in a dose-dependent fashion, so that GABA might have reduced gap junction communication between SCN neurons via the GABAA receptor [ 14 ] . In that study they could not clarify how the activation of a GABAA receptor and subsequent increase in chloride conductance impact gap junctions.

  • Work in this laboratory has shown lags in neuromuscular development associated with excessive zinc exposure during neural tube formation and, possibly, accompanying narrowing of the vertebral arches [ 26 ] . Another curious finding of this study is that widening of the vertebral arch occurs with either the GABAa agonist muscimol or the antagonist bicuculline.

  • In studies, it has been reported that increases in intracellular Ca +2or decreases in intracellular pH can uncouple cells [ 15 ] . So they suggest that a participation of the GABA receptors in the regulation of Ca +2concentration or intracellular pH could explain the uncoupling effect of muscimol.

  • Depolarization propagation was also inhibited by muscimol, a GABA A receptor agonist, in a dose dependent manner, and inhibition was reversed by bicuculline, a GABA A receptor antagonist.

  • Secondly, muscimol might increase the chloride conductance independent of gap junctions, and might cause a decrease in the spread of depolarization.


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