Words similar to muscimol

Example sentences for: muscimol

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The GABAa agonist muscimol produced a significant widening of the vertebral arch at all three doses tested (1, 2, 4 mg/kg) (p=.
In studies, it has been reported that increases in intracellular Ca +2or decreases in intracellular pH can uncouple cells [ 15 ] . So they suggest that a participation of the GABA receptors in the regulation of Ca +2concentration or intracellular pH could explain the uncoupling effect of muscimol.
Depolarization propagation was also inhibited by muscimol, a GABA A receptor agonist, in a dose dependent manner, and inhibition was reversed by bicuculline, a GABA A receptor antagonist.
Furthermore, muscimol inhibited dye-transfer between neurons in the SCN culture in a dose-dependent fashion, so that GABA might have reduced gap junction communication between SCN neurons via the GABAA receptor [ 14 ] . In that study they could not clarify how the activation of a GABAA receptor and subsequent increase in chloride conductance impact gap junctions.
While the GABAa agonist muscimol and antagonist bicucullin widened the vertebral arch, as did the GABAb agonist baclofen, the GABAb antagonist hydroxysaclofen narrowed the vertebral arch.