Words similar to muscarinic
Example sentences for: muscarinic
How can you use “muscarinic” in a sentence? Here are some example sentences to help you improve your vocabulary:
8A) that is resistant to muscarinic blockade and a sustained part of the contraction (Phase II or plateau phase) that is very sensitive to anti-muscarinic agents [ 20 21 ] . Olanzapine at 1 and 10 mg/kg reduced the amplitude of Phase I to 79 and 74% of the control values, respectively (Fig.
In fact, clozapine has a greater affinity for muscarinic receptors than olanzapine [ 11 ] and clozapine was also able to decrease the EMG and abolish the bursting pattern during phase 2.
administration of muscarinic antagonist (atropine [ 16 ] ) or i.t.
In addition to the binding sites for natural or endogenous agonists (orthosteric sites), many GPCRs have also been found to have allosteric sites [ 35 ] . These sites can bind natural ligands, as in the case of Zn ions and heparin for the dopamine and neurokinin receptors, respectively, or bind synthetic drugs such gallamine, in the case of the muscarinic receptors [ 35 ] . Binding of small molecules to these allosteric sites can modulate activity of a receptor without directly mimicking or competing out the interaction of ligands to the orthosteric sites.
2 ml into the bladder the distal, cut end of the pelvic nerve was stimulated with a long train (5 Hz; 1 msec pulse width; 60 sec train; 30-300 (uamps) to elicit a prolonged contraction displaying two phases: Phase I, a rapid contraction and Phase II, a plateau phase [ 20 21 ] . Phase I is resistant to atropine, and therefore is mostly due to non-adrenergic, non-cholinergic activation, whereas Phase II is highly sensitive to muscarinic blockade [ 21 ] . Olanzapine (n = 4) and risperidone (n = 4) were administered (0.
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