Example sentences for: morphogenic

How can you use “morphogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It has been hypothesized that statins mediate their effects by increasing the expression in bone of the growth factor bone morphogenic protein-2 (BMP-2) which in turn leads to osteoblast differentiation and bone formation [ 2 ] . This mechanism of action has been addressed by Baumann et al.

  • We postulate that myeloblastin in our model system may negatively regulate EC activation, thereby signaling to end EC morphogenic differentiation.

  • HGF/SF induces mitogenic and morphogenic changes, including rapid membrane ruffling, formation of microspikes, and increased cellular motility [ 12 13 ] . The diverse biological effects of HGF/SF are all mediated by Met, which is preferentially expressed on epithelial cells [ 14 ] . In vivo this receptor-ligand pair is essential for normal embryonic development [ 15 16 ] . Whereas Met signaling clearly has a role in normal cellular processes, this signaling pathway has also been implicated in tumor development and progression.

  • Intracellular signaling machinery of adenylyl cyclase is required for cytoskeletal organization, vessel maturation, and vessel integrity [ 24 ] . PF4 is a chemokine that binds to FGF and is a known inhibitor of EC proliferation and migration [ 25 ] . Thus, the upregulation of PF4 might limit the degree of activation of ECs and morphogenic differentiation.

  • The sequence and timing of morphogenic events in the C57BL/6J and A.BY/SnJ mouse strains is summarized in Figure 1, and is similar to that for rats [ 31].


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