Example sentences for: monokines

How can you use “monokines” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Interestingly, the analysis of abstract contents was able to distinguish monokines belonging to the CXCR family (SCYB chemokines: IP-9, IP-10, MIG; associated with 'CXC', 'CXCR', 'monokine' or 'MIG') from CC chemokines (SCYA chemokines: LARC, RANTES, MCP2, MCP3).

  • With the description of lymphocyte-derived growth factor activities in the 1960s and 1970s, it was realized that activated lymphocytes secrete soluble factors that are critical for subsequent lymphocyte proliferation [ 2 3 ] . Moreover, in 1967 it was demonstrated that monocytes or macrophages serve as necessary accessory cells for the lymphocyte activation process [ 4 ] . Then, in the early 1970s several reports indicated that mitogen- or endotoxin-stimulated macrophages release soluble lymphocyte activating factors (LAFs) that also amplify the activation process [ 5 6 ] . Accordingly, lymphokines and monokines, which collectively came to be known as cytokines, became prime research subjects for those interested in lymphocyte activation [ 7 8 ] . However, it was not until the 1980s that the cell surface and soluble molecules responsible for the complex cellular changes of lymphocyte activation were identified.


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