Words similar to modelling

Example sentences for: modelling

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Our comparative modelling methods produce excellent models when the percentage identity between the target and corresponding template sequence is high (usually within 2.0 Å C α RMSD for > 30% identity).
Historically, in comparative modelling, the template with the highest sequence identity or similarity to the target sequence being modelled has been used for further analysis.
CASP1 was an eye-opener in terms of understanding the difficulty of making accurate predictions on approximate templates in comparative modelling [ 14 ] . The main problems in creating a good comparative or fold recognition model were related to alignment between the template and target sequences, and building of non-conserved variable regions (side chains, and main chain loops).
Comparative modelling and fold recognition
Even though our methods produced mediocre results at CASP1, we realised that a major problem with accurate comparative modelling had to do with the interconnected nature of protein structures [ 23 ] : If a certain region of the protein varied with respect to the homologue, then it was likely that a structurally interacting region would also vary, even if that region was conserved in sequence.