Words similar to midas
Example sentences for: midas
How can you use “midas” in a sentence? Here are some example sentences to help you improve your vocabulary:
The domain contains a full set of MIDAS sequence motifs consisting of hhhhDxSxS, followed after ~70 residues by a conserved threonine, followed after a further ~30 residues by hhhh[S,T]DG, where h is any hydrophobic residue and x is any residue (Fig.
The initial step of the insertion can proceed in the presence of either Mg.ATP or a non-hydrolyzable ATP-analog and involves oligomerization of the BchD and BchI subunits to form an oligomeric ring of AAA protomers that resembles the ring structure of NSF and other AAA proteins [ 14 32 ] . The second step of the insertion involves an obligatory hydrolysis of ATP that is tightly coupled with the transfer of the chelated Mg 2+to the protoporphyrin ring by BchH [ 49 ] . Although the details differ from midasin, particularly with respect to the subunit composition of the AAA ring, this chelation reaction provides a structural model suggesting that the function of the midasin M-domain may be to regulate the ATPase activity of the AAA protomers in the pseudo-hexameric ring and thus couple ATP hydrolysis to the binding of a protein ligand at the MIDAS site.
At critical points in her life, she chose brilliant and charismatic men to marry (Phil, president of the Harvard Law Review ), hire (Bradlee--well, Bradlee is Bradlee), or go into business with (Buffett, the modern Midas).
The legend of King Midas has been generally misunderstood.
One possibility is that the MIDAS site serves to attach protein ligands through a mechanism involving participation of a glutamate or aspartate residue on the ligand in the coordination of a Mg 2+ion at the MIDAS site of midasin, in a manner similar to that by which the MIDAS site in integrin I-domains appears to mediate attachment of collagen through the glutamate in the GFOGER binding motif [ 36 ] . Interestingly, the related RGE ligand-binding motif [ 41 ] occurs in a conserved region of the midasin AAA-domain (yeast, residues 1835-1838), as well as in the AAA-domain of Mg chelatases [ 32 ] . The presence of this consensus binding motif in the AAA domain raises the possibility of the midasin molecule folding back onto itself, with the M-domain becoming attached to one face of the AAA domain and perhaps regulating access to its central chamber, in a manner analogous to that in which the 19S proteasome regulator, also an AAA protein, controls access to the central proteolytic chamber of the proteasome [ 42 ] .
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