Example sentences for: microtubule

How can you use “microtubule” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Initial analysis of approximately 157,000 SAGE tags from PC12 cells cultured without or with NGF for 9 days revealed nearly 800 transcripts (of a total of at least 21,000) that are regulated by ± 6-fold or greater in response to NGF [ 11 ] . Of these, approximately 150 were assignable to named genes of known functions that regulate cellular behaviors ranging from actin and microtubule cytoskeleton assembly/disassembly, gene transcription, RNA processing, neurotransmission, and energetics.

  • To test whether checkpoint mutants are sensitive to microtubule depolymerization drugs, we spotted serial dilutions of cultures on plates containing 20 mg/ml TBZ.

  • To ensure that arginine-Sepharose chromatography did not preferentially fractionate specific tubulin isotypes, microtubule protein fractions from an early stage in purification (tubulin plus MAPs) were examined by ELISAs and Western blotting.

  • For example, total amounts of polymerizable tubulin are decreased in paclitaxel-resistant cells, whereas col-cemid-resistant tubulin or vinca alkaloid-resistant cells have increased levels of assembled tubulin [ 34 66 67 ] . Furthermore, when cells were transfected with β-tubulin class III, weak resistance to paclitaxel was found, and this resistance was associated with decreased microtubule stability [ 68 ] . This is consistent with the different modes of action of these drugs: paclitaxel stabilizes microtubules and colcemid inhibits tubulin assembly.

  • Most of the benign mutations are located on the front or back of the FtsZ subunit, i.e., the faces corresponding to the outside or inside of the microtubule (Fig.


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