Words similar to microtubules
Example sentences for: microtubules
How can you use “microtubules” in a sentence? Here are some example sentences to help you improve your vocabulary:
There are reports of tubulin isotypes that are differentially incorporated into microtubule structures [ 62 ] . However, it is not possible to fractionate microtubules from total cytoplasmic tubulin with quick-frozen human tissue samples.
These include: quin2-AM (intracellular [Ca 2+]), herbimycin A (tyrosine kinases), chelerythrine (PKC), cytochalasin D (actin microfilaments), and nocodazole (disassembly of microtubules).
Although DOTMAC induced bundling of actin filaments and microtubules, which could have affected ultrastructural features of the cytoskeleton, microextensions of DOTMAC/PFA-extracted cells did not differ from those of non-treated cells.
There is no indication that any of these joining polypeptides contains a ATP-sensitive microtubule-binding site resembling that located between the AAA4 and AAA5 protomers of dynein [ 46 ] . The position of the N-terminal domain of midasin relative to the AAA domain is similar to that of the stem domain of dynein, and in several organisms the midasin N-terminal domain contains a cluster of basic residues that has the potential to bind microtubules in an ATP-insensitive manner.
For example, total amounts of polymerizable tubulin are decreased in paclitaxel-resistant cells, whereas col-cemid-resistant tubulin or vinca alkaloid-resistant cells have increased levels of assembled tubulin [ 34 66 67 ] . Furthermore, when cells were transfected with β-tubulin class III, weak resistance to paclitaxel was found, and this resistance was associated with decreased microtubule stability [ 68 ] . This is consistent with the different modes of action of these drugs: paclitaxel stabilizes microtubules and colcemid inhibits tubulin assembly.
Loading...