Words similar to micronized
Example sentences for: micronized
How can you use “micronized” in a sentence? Here are some example sentences to help you improve your vocabulary:
CAP in micronized form and formulated into a cream, is a broad spectrum microbicide inactivating several sexually transmitted disease (STD) pathogens [ 2 3 4 ] , including HIV-1 [ 2 5 ] . It was of interest to explore the mechanism(s) whereby CAP causes inactivation of HIV-1.
In order to correlate the properties of CAP in soluble and micronized forms, it was necessary to establish whether or not micronized CAP would bind HIV-1 virus particles and HIV-1 envelope glycoproteins, and induce the formation of gp41 six-helix bundles, a marker of irreversible virus inactivation, as did soluble CAP [ 37 ] . First it was established that HIV-1 gp120 bound to micronized CAP (provided in the form of micronized CAP particles or of a commercial product, "Aquateric", containing about 66% of CAP and used for enteric coating of tablets and capsules in the pharmaceutical industry [ 54 ] ); (Fig.
The interaction between HIV-1 IIIB, a representative of X4 viruses, and HIV-1 BaL, a representative of R5 viruses, with the micronized form of CAP has the following consequences: 1) elicitation of "dead-end" gp41 six-helix bundles expected to render the virus incompetent to fuse with target cells; 2) loss of virus integrity and stripping off of the envelope glycoproteins; and 3) inactivation of virus infectivity.
Elicitation of gp41 six-helix bundles and virucidal activity represent shared properties between micronized and soluble (at sufficient concentrations) forms of CAP [ 37 ] .
This suggests that interaction of virus particles with micronized CAP resulted in stripping off of the viral envelopes which was more noticeable with HIV-1 BaL than with HIV-1 IIIB.
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