Example sentences for: micrometastases

How can you use “micrometastases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • None of the 81 sections of mammary carcinoma sentinel lymph nodes showed immunoreactivity for the cocktail in any of the non-melanoma cells (Figure 2C) and were interpreted as negative for melanoma micrometastases by all five observers.

  • However, as demonstrated in our previous study, it is not uncommon to face an equivocal situation when S-100 protein is used as an immunomarker for the interpretation of single melanoma micrometastases in sentinel lymph nodes [ 6 ] . Based on our previous study with HMB45 [ 6 ] and an initial study with micropthalmia transcription factor [ 22 ] , these immunomarkers were not considered suitable for inclusion in the cocktail due to the immunoreactivity of non-melanoma cells in the sentinel lymph nodes.

  • At present histomorphologic examination with immunohistochemistry remains the most reliable and practical means of detecting melanoma micrometastases in sentinel lymph nodes [ 6 21 ] . MART-1 and Melan-A are two antibodies to different epitopes of the same antigen and are complementary to each other.

  • In general, the micrometastases were subtle and difficult to detect in the hematoxylin and eosin stained sections alone.

  • Out of 188 sections immunostained with the cocktail and interpreted by all five pathologists collectively, 41 were positive for melanoma micrometastases (Figure 2Aand 2B).


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