Example sentences for: micromolar

How can you use “micromolar” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • PPARs are nuclear hormone receptors that are activated by micromolar concentrations of various FAs and FA analogues, such as fibrates and thiazolidinediones [ 29 ] . This subfamily can be divided into three isotypes, designated PPARα, PPARδ and PPARγ, each with tissue-specific expression.

  • 68 μM) after treatment with 25-600 mg /day [ 4 ] . In our system, the level of Gleevec at the tested concentration was in the low micromolar ranges, and the inhibitory effect of Gleevec on A549 cells is likely to be genuine through binding to the receptor, not due to the toxic effects of the drug.

  • The middle histidine of the histidine triad (His96 in human Fhit), which is critical for hydrolysis of ApppA by Fhit [ 14 16 ] , is not necessary for tumor suppression [ 17 18 ] . Nonetheless, wild-type and His96Asn forms of Fhit are saturated by ApppA in the low micromolar range and form stable complexes with non-hydrolyzable ApppA in which two ApppA analogs are bound per Fhit dimer and all phosphates cluster on one surface of the protein [ 16 ] . These observations suggested that Fhit-substrate complexes may be the active, signaling form of Fhit and that the function of the catalytically essential histidine may be to terminate the lifetime of signaling complexes [ 16 ] .

  • In addition, the synthetic forms of KcC7, KcD11, KcF6 and the recombinant KcF12 (rKcF12) were able to compete the binding of TNFα and TNFβ, as well as KcF6 and KcF12 phage clones in the micromolar range (unpublished data).

  • Various amounts of [ 3H]thiamine (to give submicromolar and micromolar final concentrations) were added and the reactions were incubated for 30 min.


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