Words similar to microglia
Example sentences for: microglia
How can you use “microglia” in a sentence? Here are some example sentences to help you improve your vocabulary:
The possibility that domoic acid may activate neonatal microglia both in vitro and in vivo is suggested by recent observations with kainic acid, a domoic acid and glutamate analog that can induce upregulation of neonatal microglia scavenger receptor mRNA [ 22 ] and tissue plasminogen activator release [ 23 ] . The putative molecular explanation for these observations has been that kainic acid activates the ionotropic AMPA glutamate GluR4 subunit which has recently been shown to be expressed by activated microglia following transient forebrain ischemia in vivo [ 24 ] . Because this subunit of the AMPA glutamate receptor has affinity for domoic acid [ 25 26 27 ] , we hypothesized that domoic acid might activate neonatal microglia in vitro and lead to concomitant mediator release [ 21 ] .
Activation of microglia has been shown to cause the release of cytokines such as TNF-α [ 7 8 ] . As shown in Fig.
Results indicated that both cholesterol oxides caused an increase in c-jun in microglia, with 25-OH-cholesterol showing a more pronounced increase (Fig.
To isolate rat neonatal microglia, cerebral cortices of 1-2 day-old Sprague-Dawley rats purchased from Harlan (Indianapolis, IN) were surgically removed and placed in cold DMEM + 10% FBS +120 U/ml P and 12 μg/ml S, the meninges carefully removed, and brain tissue minced and dissociated with trypsin-EDTA at 36°C for 3-5 min.
.. " [ 32 ] . Interestingly, because rat neonatal microglia have been shown to express BDNF [ 57 ] and bFGF [ 58 ] , and in view of the fact that LPS can affect BDNF gene expression in rat neonatal microglia cells [ 59 ] , experiments are currently underway in our laboratory to determine if domoic acid may affect neonatal rat microglia expression of both BDNF and bFGF.
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