Words similar to microglia
Example sentences for: microglia
How can you use “microglia” in a sentence? Here are some example sentences to help you improve your vocabulary:
also been observed after a 2 hour stimulation of rat neonatal microglia with kainic acid, a domoic acid and glutamate analog [ 41 ] . Taken together, our results with domoic acid as well as those of Noda et al.
Microglia constitute the main leukocyte-dependent source of reactive oxygen species in the central nervous system [ 55 ] . Since microglia were first shown to release O 2 - [ 6 ] numerous investigations have been undertaken over the past 14 years to characterize agents than can either prime and/or trigger the microglia O
Prior to testing our hypothesis experimentally, and determining whether domoic acid had the potential to directly activate rat neonatal microglia in vitro, we thought that it was of critical importance to establish that: (1) the domoic acid preparation used in these experiments was stable, (2) rat neonatal microglia isolated by our methodology expressed the AMPA glutamate receptor GluR4 subunit which has been observed in activated rat microglia in vivo [ 24 ] and, (3) to confirm that the domoic acid concentration selected for our in vitro studies with rat neonatal microglia was one that was clearly toxic to neuronal cells in vitro after a short-term exposure.
Futhermore immuno-PCR techniques, which have allowed investigators to study the kinetics of TNF-α release at the femtomolar range [ 48 ] , might help to study the kinetics of picomolar microglia TNF-α release triggered by a short-term exposure to domoic acid.
Consistent with this idea, results from this study suggest that an unfavorable balance of the JNK and ERK causes the cell death observed in cholesterol oxide treated microglia.
Loading...