Words similar to microglia
Example sentences for: microglia
How can you use “microglia” in a sentence? Here are some example sentences to help you improve your vocabulary:
Having determined that our domoic acid preparation was stable and undegraded, that rat neonatal microglia expressed GluR4 in vitro and that 1 mM domoic acid was toxic to cerebellar granule neurons in vitro but did not affect the viability of rat neonatal microglia, we then investigated whether a short term 1-6 hour exposure to 1 mM domoic acid would activate rat neonatal microglia in vitro.
We have recently reported on the kinetics of LPS activation of rat neonatal microglia and the concomitant release of TNF-α protein, MMP-9 and O 2 - [ 7 ] . These three microglia mediators are currently thought to participate in neuronal and glial injury in vivo [ 10 45 ] .
.. " [ 32 ] . Interestingly, because rat neonatal microglia have been shown to express BDNF [ 57 ] and bFGF [ 58 ] , and in view of the fact that LPS can affect BDNF gene expression in rat neonatal microglia cells [ 59 ] , experiments are currently underway in our laboratory to determine if domoic acid may affect neonatal rat microglia expression of both BDNF and bFGF.
[ 21 ] ), a growing body of research also suggests that there might be increased vulnerability during the neonatal period [ 15 16 17 ] . The fact that the blood-brain barrier is incomplete [ 34 ] , provides a putative explanation as to why neonates and fetal mice in utero appear to be more sensitive to neurotoxins like domoic acid than adult animals [ 35 36 37 ] . Although microglia contribute to circa 10% of the total glial cell population in the central nervous system (For review see Ref.
Microglia constitute the main leukocyte-dependent source of reactive oxygen species in the central nervous system [ 55 ] . Since microglia were first shown to release O 2 - [ 6 ] numerous investigations have been undertaken over the past 14 years to characterize agents than can either prime and/or trigger the microglia O
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