Words similar to microfibrils

Example sentences for: microfibrils

How can you use “microfibrils” in a sentence? Here are some example sentences to help you improve your vocabulary:

The MFS phenotype is the result of mutations in FBN1, a large gene composed of 65 exons encoding the 350 kD fibrillin-1 protein that is the major constituent of microfibrils in the extracellular matrix (reviewed in [ 3 ] ). To date, 201 unique FBN1 mutations have been identified, including 70 (34.
Immunoprecipitation studies with fibrillin-specific antibodies revealed the presence of a 15 kD-smaller mutant polypeptide in the medium of metabolically labeled mutant fibroblasts [ 7 ] . The shortened molecule was incorporated into the extracellular matrix and apparently caused major disruptions of microfibrils [ 23 ] .
Both mutations lead to the synthesis of mutant FBN1 proteins that interfere with microfibril assembly, resulting in significantly reduced extracellular matrix microfibrils.