Words similar to microfibrils

Example sentences for: microfibrils

How can you use “microfibrils” in a sentence? Here are some example sentences to help you improve your vocabulary:

The MFS phenotype is the result of mutations in FBN1, a large gene composed of 65 exons encoding the 350 kD fibrillin-1 protein that is the major constituent of microfibrils in the extracellular matrix (reviewed in [ 3 ] ). To date, 201 unique FBN1 mutations have been identified, including 70 (34.
Both mutations lead to the synthesis of mutant FBN1 proteins that interfere with microfibril assembly, resulting in significantly reduced extracellular matrix microfibrils.
Immunoprecipitation studies with fibrillin-specific antibodies revealed the presence of a 15 kD-smaller mutant polypeptide in the medium of metabolically labeled mutant fibroblasts [ 7 ] . The shortened molecule was incorporated into the extracellular matrix and apparently caused major disruptions of microfibrils [ 23 ] .