Words similar to microfilaments
Example sentences for: microfilaments
How can you use “microfilaments” in a sentence? Here are some example sentences to help you improve your vocabulary:
The mechanism underlying this cytoskeletal rearrangement due to shear stress is ill-defined, but it has been found to be linked to tyrosine kinase activity, levels of intracellular calcium, intact actin microfilaments, and functional microtubule network, but is independent of protein kinase C, intermediate filaments, and stretch- and shear-activated mechanosensitive K +channels [ 28].
Our data suggest that while many mRNAs distribute equally between the cytosolic and cytoskeletal fractions, a specific set of transcripts associates preferentially with actin microfilaments.
Latrunculin B depolymerizes actin microfilaments and hence should release components that normally associate with the actin cytoskeleton.
To depolymerize actin microfilaments, cells were treated with 0.1 μg/ml latrunculin B (Cytoskeleton, Inc.) 30 min prior to harvest.
The involvement of Rho GTPases in regulating integrin dependent events such as leukocyte homotypic aggregation and in chemokine upregulation of integrin-mediated adhesion has recently been identified [ 18 19 ] . ADP-ribosylation of Rho in neutrophils by treatment with C3 not only inhibits cellular locomotion, but augments chemoattractant induced actin polymerization [ 20 21 ] . Moreover, inactivation of Rho in monocytic cells leads to accelerated formation of filopodia, and it has been proposed that Rho is a negative regulator of actin polymerization within this cell type [ 22 ] . Active Rho is also required for normal morphology, motility, and cytolytic activity of IL-2 activated NK cells [ 23 24 ] . We and others have demonstrated the importance of Rho in T lymphocyte activation [ 25 26 ] . Given the role played by Rho in the regulation of actin microfilaments in other cell types, and the indispensability of a functional actin cytoskeleton in lymphocyte motility and activation, it is of importance to study Rho's role in the regulation of T lymphocyte integrin function and maintenance of cytoskeletal organization.
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