Words similar to microfilaments
Example sentences for: microfilaments
How can you use “microfilaments” in a sentence? Here are some example sentences to help you improve your vocabulary:
The involvement of Rho GTPases in regulating integrin dependent events such as leukocyte homotypic aggregation and in chemokine upregulation of integrin-mediated adhesion has recently been identified [ 18 19 ] . ADP-ribosylation of Rho in neutrophils by treatment with C3 not only inhibits cellular locomotion, but augments chemoattractant induced actin polymerization [ 20 21 ] . Moreover, inactivation of Rho in monocytic cells leads to accelerated formation of filopodia, and it has been proposed that Rho is a negative regulator of actin polymerization within this cell type [ 22 ] . Active Rho is also required for normal morphology, motility, and cytolytic activity of IL-2 activated NK cells [ 23 24 ] . We and others have demonstrated the importance of Rho in T lymphocyte activation [ 25 26 ] . Given the role played by Rho in the regulation of actin microfilaments in other cell types, and the indispensability of a functional actin cytoskeleton in lymphocyte motility and activation, it is of importance to study Rho's role in the regulation of T lymphocyte integrin function and maintenance of cytoskeletal organization.
These include: quin2-AM (intracellular [Ca 2+]), herbimycin A (tyrosine kinases), chelerythrine (PKC), cytochalasin D (actin microfilaments), and nocodazole (disassembly of microtubules).
Latrunculin B depolymerizes actin microfilaments and hence should release components that normally associate with the actin cytoskeleton.
Use of selective signaling pathway inhibitors allowed the demonstration that the cytoskeletal changes elicited by resveratrol depended on intracellular calcium and tyrosine kinase activity changes, and also appeared to be linked to integrity of actin microfilaments and microtubule network.
Intact actin microfilaments were required for the localization and/or anchoring of these transcripts.
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