Example sentences for: mfold

How can you use “mfold” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Given a 100-nucleotide input sequence, mfold 3.1 typically returns one to six alternate structures, each containing one to four helical arms; thus, the structure containing the highest-scoring helical arm had to be determined for each folded sequence.

  • The mfold computer program version 3.0 http://bioinfo.math.rpi.edu/~mfold/rna/form1.cgiwas used to predict the RNA secondary structure and to calculate the folding free energy [ 26 27 ] . We have computed the minimum-free-energy structures from all the donor- and acceptor sites of the 60 exons of NF1 within a window of 100 bp.

  • We analyzed conserved regions with mfold 3.1, an RNA-folding algorithm [ 41 ] . As miRNA genes can be located on either strand, and the quality of predicted hairpin structures can vary significantly between the respective strands (depending on the amount of G-U base-pairing), we folded each region as both the forward and the reverse complement of the extracted sequence (436,000 regions × 2 = 872,000 mfolds).

  • All Dm regions were folded with mfold 3.1 by submitting parallel batches of 500 mfolds to the cluster nodes and copying the .det and .out mfold output files to a final storage destination.

  • Since mfold tends to insert small helices within terminal loops that falsely reduce the size of the terminal loop, small terminal loops (3, 4 or 5 nucleotides in length) were extended to seven nucleotides.


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