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Example sentences for: meu

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In contrast, both of the modified pyrimidine triphosphates (MeC and MeU) tested resulted in a decrease in overall signal intensities for nearly all of the probes tested when compared against unmodified control samples (Figures 2D& 2E).
Those probes whose signal intensities were increased at least two-fold are summarized in Table 1. As Table 1shows, for a number of transcripts substitution with MeC or MeU may potentially augment hybridization signals more so than even DAP.
The fact that DAP was able to increase hybridization intensities while MeC and MeU decreased hybridization intensities (Figures 2Dand 2E) is interesting in light of the fact that DAP is a purine incorporated into an RNA strand while MeC and MeU are pyrimidines incorporated into an RNA strand.
In contrast, we were unable to examine incorporation levels of the MeU because the MeU peak was eluted at approximately the same time as the guanosine peak (data not shown).
Although DAP, MeC, and MeU were tolerated by T7 RNA polymerase, incorporation of these analogs into our IVT reaction cocktails reduced the yields of amplified cRNA.