Words similar to mecp
Example sentences for: mecp
How can you use “mecp” in a sentence? Here are some example sentences to help you improve your vocabulary:
There were no significant differences in percent "present" calls between MeCP2-deficient and MeCP2-positive samples.
Fourth, MeCP2 action on chromatin, as suggested by observed changes in histone acetylation [ 31 32 ] , may not involve protein coding genes that are represented on microarrays, but instead, may affect centromeric heterochromatin or the expression of small non-coding RNAs that are abundant in normal brain [ 33 ] . The results presented in this paper contradict the established model of MeCP2 function and necessitate a rethinking of strategies to unravel the pathologic process that leads to neuronal dysfunction in Rett syndrome.
To identify potential downstream targets of MeCP2 modulation, we have compared global gene expression patterns in four matched pairs of clonally derived mutant or wild-type MECP2-expressing fibroblast cell strains from girls with Rett syndrome, and in five wild-type and four mutant MeCP2-expressing lymphoblastoid cell lines, by hybridizing Affymetrix U95 (A-E) oligonucleotide microarrays.
Absence of DNA contamination was verified by amplifying the 756 bp intron containing region of the MECP2 gene between exons 3 and 4 using exon 3 based primer 5'-AGCCCGTGCAGCCATCAGCC-3' and exon 4 based primer 5'-CTTCCCAGGACTTTTCTCCA-3'.
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