Words similar to mecp

Example sentences for: mecp

How can you use “mecp” in a sentence? Here are some example sentences to help you improve your vocabulary:

To identify potential downstream targets of MeCP2 modulation, we have compared global gene expression patterns in four matched pairs of clonally derived mutant or wild-type MECP2-expressing fibroblast cell strains from girls with Rett syndrome, and in five wild-type and four mutant MeCP2-expressing lymphoblastoid cell lines, by hybridizing Affymetrix U95 (A-E) oligonucleotide microarrays.
We hypothesized that the effects of MeCP2 dysfunction in the mutant clonal cell strain would be more pronounced than in the original cell strain with mosaic X chromosome inactivation.
While our initial matched fibroblast clonal comparisons identified numerous genes with consistent results that could be targets of MeCP2 modulation, verification of a small subset of these data by comparing additional clones not used on the GeneChip ®analysis revealed amazing inconsistency.
Absence of DNA contamination was verified by amplifying the 756 bp intron containing region of the MECP2 gene between exons 3 and 4 using exon 3 based primer 5'-AGCCCGTGCAGCCATCAGCC-3' and exon 4 based primer 5'-CTTCCCAGGACTTTTCTCCA-3'.
Cell clones expressing an allele with a truncating mutation (FB 705delG, FB 1155del32, LCL R168X), do not produce a normal sized MECP2 protein.