Example sentences for: mecp

How can you use “mecp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • There were no significant differences in percent "present" calls between MeCP2-deficient and MeCP2-positive samples.

  • Fourth, MeCP2 action on chromatin, as suggested by observed changes in histone acetylation [ 31 32 ] , may not involve protein coding genes that are represented on microarrays, but instead, may affect centromeric heterochromatin or the expression of small non-coding RNAs that are abundant in normal brain [ 33 ] . The results presented in this paper contradict the established model of MeCP2 function and necessitate a rethinking of strategies to unravel the pathologic process that leads to neuronal dysfunction in Rett syndrome.

  • To identify potential downstream targets of MeCP2 modulation, we have compared global gene expression patterns in four matched pairs of clonally derived mutant or wild-type MECP2-expressing fibroblast cell strains from girls with Rett syndrome, and in five wild-type and four mutant MeCP2-expressing lymphoblastoid cell lines, by hybridizing Affymetrix U95 (A-E) oligonucleotide microarrays.

  • Absence of DNA contamination was verified by amplifying the 756 bp intron containing region of the MECP2 gene between exons 3 and 4 using exon 3 based primer 5'-AGCCCGTGCAGCCATCAGCC-3' and exon 4 based primer 5'-CTTCCCAGGACTTTTCTCCA-3'.


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