Words similar to mec
Example sentences for: mec
How can you use “mec” in a sentence? Here are some example sentences to help you improve your vocabulary:
In contrast, both of the modified pyrimidine triphosphates (MeC and MeU) tested resulted in a decrease in overall signal intensities for nearly all of the probes tested when compared against unmodified control samples (Figures 2D& 2E).
Could the differential effects of DAP versus MeC or MeU or the differential effects of DAP on different probe sequences also be related to structural consequences?
However, data points on the right of the diagonal in figures 2Dand 2Ealso show that for a fractional set of target-probe pairs, substitution with MeC and MeU increased hybridization signal relative to the unmodified control.
Finally, earlier studies have noted that methylation of cytosines (generating MeC) in ribopolynucleotides stabilizes duplexes to the same extent as substitution of thymine (MeU) for uracil [ 28 ] . Thus, although it is still surprising that MeC and MeU decrease hybridization intensities, it is not surprising that the magnitude of the effects generated by MeC and MeU residues are similar.
Naturally occurring analogs of purine and pyrimidine bases have been examined extensively for their ability to increase the thermodynamic stability of DNA:DNA and DNA:RNA duplexes [ 11 12 13 14 15 ] . Among these are 2-aminoadenine also known as diaminopurine (DAP), which is found in S-2L cyanophage DNA [ 16 ] , 5-methyl uracil (MeU), and 5-methyl cytidine (MeC).