Words similar to mec
Example sentences for: mec
How can you use “mec” in a sentence? Here are some example sentences to help you improve your vocabulary:
Many studies have shown that a ribopurine rich strand bound to a deoxypyrimidine rich strand has a higher stability than the corresponding all deoxy strands which, in turn, have a higher stability than a deoxypurine rich strand bound to a ribopyrimidine rich strand [ 26 27 ] . These differences also suggest that further studies examining DAP or MeC incorporation into first strand cDNA, followed by formation of a DNA-DNA duplex, may not necessarily show the same effects as incorporation of these modified nucleotides into cRNA.
Could the differential effects of DAP versus MeC or MeU or the differential effects of DAP on different probe sequences also be related to structural consequences?
Finally, earlier studies have noted that methylation of cytosines (generating MeC) in ribopolynucleotides stabilizes duplexes to the same extent as substitution of thymine (MeU) for uracil [ 28 ] . Thus, although it is still surprising that MeC and MeU decrease hybridization intensities, it is not surprising that the magnitude of the effects generated by MeC and MeU residues are similar.
Although DAP, MeC, and MeU were tolerated by T7 RNA polymerase, incorporation of these analogs into our IVT reaction cocktails reduced the yields of amplified cRNA.
DNA repair activities may take place at these foci since BRCA1 has been shown to co-localize with ATR in damage-induced foci [ 58 ] . Using elegant methods to test for direct association of DNA damage checkpoint proteins at double strand breaks in vivo , other groups have shown that MEC1 Rad3-HA and LCD1 Rad26-GFP localize to sites of DNA damage [ 59 60 ] . However, MEC1 was required for this re-localization of LCD1-GFP in vivo [ 60 ] . Thus, while re-localization of Rad26/Rad3-related complexes to sites of DNA repair may be evolutionarily conserved, the regulation of these complexes is not.
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