Example sentences for: methodologies

How can you use “methodologies” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Different methodologies and strategies for reducing noise include establishing an arbitrary global threshold for fold-changes [ 9 ] , noise-filtering look up tables [ 8 ] , normalization techniques to make microarrays comparable, such as using ANOVA methods to provide estimates of changes in gene expression that are corrected for potential confounding effects [ 10 11 ] , and using replicate experiments to estimate the variability in reported gene expression [ 12 ] . Applying fold change thresholds has been the most common method of reducing noise by filtering out the false positives [ 8 9 13 ] . However, much of the work done to date has focused on decreasing noise within the same generation and has not addressed the issue of comparability across generations.

  • Methodologies for large-scale molecular profiling of disease tissues have been well established [ 1 2 3 ] and have been shown to be of utility both diagnostically [ 4 ] and prognostically [ 5 ] . However, application of such approaches in the assessment of changes induced by cancer therapeutic agents in solid tumors in man has been hindered by limited accessibility or availability of tumor tissue at multiple time points during treatment.

  • Table 1compares features of iGAP with those of GeneQuiz and PEDANT, two established genome annotation methodologies.

  • This is important because it has been suggested that because of the high degree of sequence similarity (97%) between the CaT1 and ECaC1 genes care should be taken in interpreting data obtained by hybridization, PCR or other methodologies based on nucleotide sequences [ 24 ] . First, the PCR product derived from the putative ECaC1 or CaT1 gene was purified and sequenced.

  • He believed that the statement was dangerous because there are research methodologies that are related to evaluating screening and separate ones related to evaluating interventions, and we may not want to obligate tying the two together.


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