Example sentences for: methotrexate

How can you use “methotrexate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Consistent with these pre-clinical studies, the design of this phase II trial involved a fluorouracil infusion that was initiated one hour into the 2 hour high dose infusion of LV and 36 hours after the initial methotrexate dosing.

  • In Silber's patient sample, one-third of the patients were treated with the less myelosuppressive CMF (cyclophosphamide, methotrexate, fluorouracil) chemotherapy regimen, and the CAF (cyclophosphamide, doxorubicin, fluorouracil) regimen consisted of 30 mg/m 2compared with the 50 mg/m 2CAF regimen used in our validation sample.

  • methotrexate) are available to treat RA but are limited by significant toxicity requiring adjunct therapy, or are of variable efficacy.

  • [ 10 ] A vast series of pre-clinical and clinical studies have suggested 5-FU is a more active anti-tumor agent when modulated by a host of compounds including leucovorin, [ 11 12 13 ] methotrexate, [ 14 ] folinic acid, [ 15 16 ] N-phosphonacetyl-L-aspartic acid (PALA) [ 17 18 19 20 21 22 ] and recombinant interferon alfa-2a (IFNaα-2a).

  • Currently the symptoms of arthritis are managed using pharmacologic agents, including both steroidal and nonsteroidal drugs, and disease-modifying drugs such as methotrexate.


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