Example sentences for: metabolites

How can you use “metabolites” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The influx of water and metabolites into the vacuole is dependent in part on the generation of a proton motive force across the tonoplast.

  • This proliferation of the small-molecule dioxygenases is consistent with their possible role in the synthesis of secondary metabolites in these organisms [ 1, 6, 7, 30].

  • What trace minerals, vitamins, and other metabolites will we need to breed into the crops of the future to fight the causes of hidden hunger, to prevent cancer, or to enhance the immune system?

  • Meanwhile, the alpha MNs are centrally inhibited by group III and IV muscle afferents, activated by the accumulation of metabolites in the fatiguing muscle, but this is expected to come into action later than from the beginning, to further accelerate the process.

  • Organic phosphate compounds are the central metabolites of all biological systems [ 1 2 ] . Some are the basic building blocks of nucleic acids, some like ATP and GTP, are additionally, cellular energy stores, others like cAMP or cGMP are messengers in signal transduction, and, yet others, such as FAD, NAD, thiamine phosphates and pyridoxal phosphate are cofactors for a range of enzymes [ 1 2 ] . Protein domains belonging to a relatively small set of structural folds are known to bind or catalyze reactions that utilize these organic phosphate compounds (see SCOP database: http://scop.mrc-lmb.cam.ac.uk/scop/) [ 3 4 ] . Several of these folds trace back to some of the earliest phases of the evolution of the protein world, and participate in a wide range of disparate biological functions in extant proteins [ 4 5 ] . Some folds, such as the P-loop fold, the Rossmann fold and the Hsp70-like fold, have been well studied, and comprise mainly of dedicated nucleotide binding or hydrolyzing proteins [ 6 7 8 9 ] . Others, such as the palm-domain, which is found in adenylyl cyclases and various nucleic acid polymerases, belong to more generalized protein folds that contain representatives with diverse biochemical activities [ 4 10 11 ] . Current availability of extensive genome sequence data, allows one to identify less numerous, nevertheless biological important organic phosphate-binding domains that may have previous eluded detection.


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