Example sentences for: metabolites

How can you use “metabolites” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although we attempted to keep the mice continuously hypoxic, a relatively brief period of reoxygenation might account for the slight increase in plasma NO metabolites seen in the hypoxic animals, which is consistent with the observations of Sato et al.

  • Several active research programs are investigating the risk associated with serum estrogens, gonadotropins and urinary sex hormone metabolites for a variety of diseases including breast cancer [ 1 ] , endometrial cancer [ 2 ] , and osteoporosis [ 3 ] . The results of the few published studies suggest that the natural temporal variability (true variation over time, not variation due to storage or other factors) of some serum estrogens, gonadotropins and urinary sex hormone metabolites is sufficiently great that a single measurement occasion may be inadequate to ensure a reliable estimate [ 4 5 6 ] . Published intraclass correlation coefficients (ICC) vary between 0.06 and 0.62 for estradiol (E 2 ) and between 0.52 and 0.69 for estrone (E 1 ) [ 4 ] . Only the percent of free E 2 and of SHBG-bound E 2 have been found to be sufficiently reliable to account for as much as 50% of the variance in the true mean ( ICC > 0.7).

  • 2-Amino-3-carboxymuconate semialdehyde can be considered to be a branchpoint metabolite that either enters committed catabolism to acetyl-CoA or that enters biosynthesis to NAD +/NADP +. In the central nervous system, a number of kynurenine-pathway metabolites are neuroactive and appear to be involved in inflammatory neurological diseases [ 32].

  • Cytosolic PLA 2 specifically hydrolyzes sn-2 arachidonate from phospholipid providing the precursors for many different lipid mediators including prostaglandins and leukotrienes [ 1 2 ] . These lipid metabolites play a role in acute inflammatory responses and also regulate normal physiological processes.

  • Metabolites of cyclooxygenase play an important role in this.


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