Example sentences for: metabolite

How can you use “metabolite” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Detection of the active Simvastatin hydroxy acid metabolite in mouse serum after gavage administration

  • Similarly as described in the clinical trials, the early animal studies reported data supportive of the initial findings [ 1 4 5 6 33 34 ] . These results however, were not substantiated in later studies in rodents, where SVS had no or little effect on bone mineral density [ 26 ] . However, none of the studies has verified the actual presence of the active SVS-OH metabolite in the animal serum, as shown in this study.

  • Consider a scenario where C. psittaci has parasitized a host niche where 3-hydroxyanthranilate is a prominent metabolite, as in human macrophages [ 42].

  • In tasks requiring the use of spatial skills, a sexually dimorphic difference has been consistently demonstrated in which males reliably outperform females [ 6 7 8 9 10 11 12 ] . This sex difference is most likely due to the presence of testosterone or more likely its metabolite estradiol, in brain [ 13 14 15 16 17 18 19 20 ] . Because phytoestrogens have the ability to bind estrogen receptors and alter many of the biological responses that are evoked by physiological estrogens [ 25 39 40 41 42 43 44 45 46 ] , we determined phytoestrogens affects on VSM in adult rats.

  • Intestinal calcium absorption is increased after feeding a low calcium diet or under conditions of increased calcium needs, such as during growth, via a parathyroid hormone (PTH)-vitamin D mediated process [ 3 ] . A lowering of serum calcium levels stimulates the secretion of PTH that then activates the renal conversion of inactive 25-hydroxyvitamin D to the active hormonal metabolite 1,25-dihydroxyvitamin D. At the intestine, 1,25-dihydroxyvitamin D, acting through a nuclear receptor, stimulates transcription of vitamin D-mediated genes, including calbindin D, involved in calcium transport thereby acting as the primary hormonal regulator of active intestinal calcium transport [ 3 ] . It is thus likely that any putative key molecular player in calcium absorption, such as CaT1 or ECaC1, should be a prime target for hormonal regulation by 1,25-dihydroxyvitamin D. However, to date, neither CaT1 nor ECaC1 expression has been shown to be related to serum 1,25-dihydroxyvitamin D or vitamin D status [ 10 16 ] .


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast