Words similar to meiosis
Example sentences for: meiosis
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MG-132 is a peptide aldehyde that inhibits ubiquitin-mediated proteolysis by binding to and inactivating 20S and 26S proteasomes [ 49 62 ] . Although 1-10 μM MG-132 inhibited first polar body extrusion in rat oocytes, its activity is reversible [ 42 ] . We conducted preliminary experiments to obtain a MG-132 dose range that would transiently perturb or inhibit OM during meiosis I while enabling oocytes to complete OM following washing out of the compound.
The formation of these cytogenetic abnormalities is mediated by low-copy repeated sequences, or duplicons [ 1 ] . High sequence homology between copies presumably facilitates mispairing and unequal recombination events in meiosis.
Diverse Implications of Recombination Hotspots: The Study of Meiosis and the Mapping of Human Disease Alleles
In all sexual animals and plants, production of an egg cell involves meiosis, the complex cellular process (involving DNA replication, recombination, and two nuclear divisions) whereby one diploid nucleus (with two copies of each chromosome) becomes four genetically different haploid nuclei (each with one copy of each chromosome).
Proteasomes translocated to meiotic spindles of rat oocytes and MG-132 induced-inhibition of proteasomal activity resulted in partial segregation of chromosomes during meiosis I [ 42 ] . Moreover, defective proteasomal activity in fission yeast impaired chromosome segregation [ 38 ] .