Words similar to meioses
Example sentences for: meioses
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In female meioses of D. melanogaster , heterochromatic pairing of homologs can substitute for chiasmata to ensure bipolar spindle attachment of bivalents and subsequent distributive segregation [ 4 5 6 8 ] . Rec12 may serve a similar role in maintaining a paired (or pseudo-paired) state between achiasmatic chromosomes prior to the first meiotic division.
At present, two hypothetical mechanisms by which a Rec12-dependent signal affects MII are proposed: First, Rec12-dependent (recombination-dependent) signals might trigger a block after MI, thereby allowing cells to skip a frequently irregular MII division [ 39 ] . However, the majority of the rec12 mutant meioses show evidence of two meiotic divisions (Figure 3) and many of the meiotic diploids exhibit mixed MI and MII missegregation patterns for centromere linked markers on the three different chromosomes (Table 2).
However, only about 50% of diploid meiotic products from rec12-D15 (null) mutant meioses were heterozygous for centromere linked markers (Figure 5E), indicating that some fraction of the products were derived from precocious separation of sister chromatids (PSS) and/or MII nondisjunction (Figure 5C, 5D).
A 250-fold reduction in recombination would leave less than 0.1 crossovers per chromosome, so all three chromosomes in most of the rec12 mutant meioses are achiasmatic.
The rec12 mutant meioses are achiasmatic and would thus be expected to suffer chromosome segregation errors during meiosis I. To gain insight into this possibility, asci from meiotic cultures were stained with a DNA specific fluorescent dye (DAPI) and visualized by differential interference contrast (DIC) and fluorescence microscopy.
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