Words similar to mef

Example sentences for: mef

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The 5' flank of exon 1b was searched with TransFac for potential transcription factor binding sites [ 34 ] . Potential binding sites for three transcription factors that have been shown to play key roles in muscle gene expression were found, Sp-1, Mef2 and SRF [ 36 ] . Four potential Sp1 and two Mef2 bindings sites were found within 300 bps of the transcription start.
The proximal 5' flank of the FGFR1 gene has a similar clustering of SP-1, Mef2, and SRF sites [ 36 ] . The FGFR1 gene is expressed in terminally differentiated muscle, although at a lower level than in proliferating myoblasts [ 36 ] . The expression depends on Sp-1 sites in the proximal promoter and the binding of Sp-1 and Sp-3 to these sites.
Other notable findings point to additional signaling proteins (CAMK, p38MAPK, and AMPK) and transcription factors (PGC-1, MEF2, ATF2, PPARs) active in pathways that intersect with calcineurin–NFAT signaling [31,43,44,45,46,47,48] (see Figure 2).
The 5' flank of exon 1a, in contrast, has a more classical TA-rich promoter region, and is devoid of Sp1 and Mef2 sites (see table 4 - additional file 4).
dNTP, deoxyribonucleoside triphosphate; hnRNP heterogeneous nuclear ribonuclear protein; nt, nucleotide; LTR, long terminal repeat; MEF, mouse embryonic fibroblast; NPT, neomycin phosphotransferase; RT PCR, reverse transcriptase polymerase chain reaction.