Words similar to mefloquine

Example sentences for: mefloquine

How can you use “mefloquine” in a sentence? Here are some example sentences to help you improve your vocabulary:

[ 33 ] One of the travellers, who was concurrently taking a liver-damaging agent, sulfadoxine, [ 34 ] showed gross morphological changes in his liver which were attributed to his use of prophylactic mefloquine.
Mefloquine has been found to alter calcium flux, into and out of, isolated skeletal muscle and brain microsomes, via an inhibitory effect of the compound on the ER calcium pump and calcium release channels (IC 50 of 42-43 uM, [ 27 28 ] ). Plasma mefloquine concentrations (therapeutic dosing) may reach 21 μM [ 18 ] and the drug crosses the blood-brain barrier, accumulating to concentrations in excess of 50 and 90 μM in the brains of humans and rats respectively [ 19 20 ] . Therefore, these biochemical effects occur at concentrations within a relevant physiological range.
50 or ED 50 ) for the effects of mefloquine on neuronal viability and calcium homeostasis were calculated using Prism software.
[ 31 ] Takeshima found that of a cohort of healthy Japanese soldiers who took prophylactic mefloquine for 36 weeks without drinking alcohol, one-quarter developed symptoms compatible with liver pathology and four showed disturbed liver function.
Fold-changes (FC) in expression were defined as: = mean mefloquine expression level/mean DMSO expression level.