Words similar to mefloquine

Example sentences for: mefloquine

How can you use “mefloquine” in a sentence? Here are some example sentences to help you improve your vocabulary:

Secondly, a short in vitro exposure time is appropriate since the adverse neurological effects of mefloquine in vivo occur within 24-48 hours of the first 1-2 doses administered [ 21 22 ] .
Triggering of the UPR also results in the suppression of global protein synthesis, as PERK is activated and phosphorylates EIK2α, which can only interact with the appropriate ribosomal binding sites in an unphosphorylated state [ 11 12 ] . While the upregulated transcription of PERK is not required for its activation, it's over expression can lead to the enhanced phosphorylation (and therefore inactivity) of EIK2α [ 16 ] . Therefore, its up-regulation by mefloquine supports the hypothesis that the drug triggers an UPR.
Mefloquine does not appear to cause florid signs of liver disease.
Mefloquine is a clinically important drug, commonly used by healthy people.
also observed that mefloquine inhibited IP 3 -induced calcium release from isolated dog brain microsomes [ 5 ] . Our results do not preclude such a role for mefloquine in neuronal cells, although it would not have been possible to observe such an effect in the present study, since we investigated only the spontaneous action of mefloquine on ER calcium homeostasis.