Words similar to mefloquine

Example sentences for: mefloquine

How can you use “mefloquine” in a sentence? Here are some example sentences to help you improve your vocabulary:

Triggering of the UPR also results in the suppression of global protein synthesis, as PERK is activated and phosphorylates EIK2α, which can only interact with the appropriate ribosomal binding sites in an unphosphorylated state [ 11 12 ] . While the upregulated transcription of PERK is not required for its activation, it's over expression can lead to the enhanced phosphorylation (and therefore inactivity) of EIK2α [ 16 ] . Therefore, its up-regulation by mefloquine supports the hypothesis that the drug triggers an UPR.
Of the 516 published case reports of mefloquine adverse effects recorded in the mefloquine systematic review, 328 of the reports related to prophylactic mefloquine use, and 188 to treatment use.
[ 5 ] Conget et al reported a 30-year old previously healthy woman who experienced abdominal pain, palpitations, instability, insomnia and a fine distal tremor in her second week of mefloquine prophylaxis.
Therefore, neurons were exposed to the lowest mefloquine concentration for 24 h.
CJun is a transcription factor upregulated in response to many forms of neurological injury [ 23 ] , thus its modulation by mefloquine under conditions of cellular stress is unsurprising and does not imply a specific mechanism of action.