Words similar to macular
Example sentences for: macular
How can you use “macular” in a sentence? Here are some example sentences to help you improve your vocabulary:
Macular background leveling in images with drusen
Since we were dealing with photography, not photometry, the choice of multiplicative or additive correction attempted to preserve semi-quantitative relationships of reflectance rather than absolute levels or precise numerical relationships [ 31 ] . Further, since reflectance variability was at issue, rather than absolute levels, we considered only the most variable components: the macular luteal pigment, dealt with above, the nerve fiber layer [ 32 33 34 35 ] , and the RPE melanin [ 36 ] . The RPE melanin is denser in the fovea, and as such will reduce the reflectance of underlying drusen in much the same manner as the luteal pigment.
Color fundus photographs have been routinely employed for diagnostic purposes for many years, and fundus photo gradings are central to clinical studies of macular disease [ 1 2 ] . The natural history of age-related macular degeneration (AMD), the leading cause of blindness in the developed world [ 3 ] , is in particular tied to that of subretinal deposits known as drusen [ 4 5 6 7 8 9 10 11 12 ] . Drusen are key in the classification of AMD, hence the importance of drusen identification and measurement in clinical studies.
An experienced retinal specialist (Grader 1, CCWK) graded the corresponding 12 stereo slide pairs independently, estimating drusen areas as a percent of the central and middle subfields in categories of 0 to 10%, 10 to 25%, 25 to 50%, and greater than 50%, as specified by the International Classification System [ 1 ] . This method of stereo pair grading is known to and accepted by clinicians as the "gold standard" for quantification of macular pathology.
By adopting this unified approach to the macular reflectance problem, we avoid the multiple local thresholds used in previous approaches [ 17 18 19 20 24 25 ] . It is important to note, however, that our method is not the standard technique of shadowing by subtracting or dividing by a blur image.
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