Words similar to madcam-
Example sentences for: madcam-
How can you use “madcam-” in a sentence? Here are some example sentences to help you improve your vocabulary:
In IBD, especially Crohn's disease, MAdCAM-1 acts as the main ligand for a4b7-expressing lymphocytes and recruits these lymphocytes into the intestine where they initiate and sustain chronic inflammation.
We observed that both a short and long-acting NO donor significantly reduce TNF-α-induced expression of MAdCAM-1 expression in lymphatic endothelial cells.
We have described in vitro that exogenous IL-10 can block the expression of MAdCAM-1 in response to TNF-α, and attenuates lymphocyte adhesion to lymphatic node derived endothelium under cytokine stimulating conditions via NF-kB inhibition [ 5 ] . The purpose of the current study was to show that induction of endothelial expression of IL-10 through an IL-10 expression vector attenuates MAdCAM-1 expression in response to TNF-α and optimistically suggests the possibility of targeted Th2-cytokine gene therapy in IBD.
MAdCAM-1 (mucosal addressin cell adhesion molecule-1), IL-10 (Interleukin-10), HEV (high endothelial venular), ECAMs (endothelial cell adhesion molecules), IBD (inflammatory bowel diseases), UC (ulcerative colitis), CD (Crohn's disease), ICAM-1 (intracellular adhesion molecule 1), VCAM-1 (vascular adhesion molecule 1), NF-kB (nuclear transfection factor kB), TNF-α (tumor necrosis factor alpha), GM-CSF (granulocyte-macrophage colony-stimulating factor), GCSF (granulocute colony stimulating factor), ECL (enhanced chemiluminescence)
A strong band is detected as MAdCAM-1 transcript after stimulated with TNF-α (20 ng/ml) for 12 h.
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