Example sentences for: madcam-

How can you use “madcam-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • TNF-α (20 ng/ml) induced MAdCAM-1 expression is blocked both by the short-acting and long-acting NO donors, SperNO and DETA-NO respectively.

  • Having established a role of NO donors in the regulation of MAdCAM-1 expression by endothelial cells, we examined effects of NO donors on the adhesion of a4b7 expressing mouse lymphocyte cell line TK-1 to TNF-α-treated endothelial cultures.

  • The TK-1 lymphocyte cell line used in this assay expresses high levels of the α4β7 integrin, [ 39 41 ] which can interact with multiple ligands including mucosal addressin-1 (MAdCAM-1), as well as VCAM-1, L-selectin and fibronectin [ 42 ] . In this system, TNF-α stimulated TK-1 adhesion to SVEC4-10 endothelial cells is at least 50% MAdCAM-1 dependent [ 41 ] . SVEC monolayers were grown in 48-well plates as described, and to activate endothelium, the monolayers were incubated with TNF-α (1 ng/ml) for 24 h.

  • The density of MAdCAM-1 staining was measured by scanning the 60 kD band, using a HP ScanJet™ flatbed scanner.

  • Here, we examine the induction of MAdCAM-1 by TNF-α, and evaluated whether endogenous nitric oxide (from eNOS and iNOS), or exogenous NO (from rapid or slow-releasing NO donors) affect the expression of MadCAM-1.


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