Words similar to macrophage-derived
Example sentences for: macrophage-derived
How can you use “macrophage-derived” in a sentence? Here are some example sentences to help you improve your vocabulary:
Initially the nomenclature of IL-1 and IL-2 was created to delineate the sequential action of an assumed single macrophage-derived soluble factor (IL-1), which promoted the production of a single lymphocyte-derived factor (IL-2) [ 14 15 25 ] . However, the molecular nature of the LAF activity was never fully elucidated, even after the isolation and identification of multiple mitogen/endotoxin-stimulated macrophage-derived products, such as IL-1, IL-6, IL-12, IL-18, and Tumor Necrosis Factor-alpha (TNF-α).
It is probable that all of these macrophage-derived soluble factors together make up the activity originally ascribed to LAF.
Accordingly, it is obvious that addition of a polyclonal activating ligand such as phytohemagglutinin to peripheral blood mononuclear cells (PBMCs) leads to the activation of soluble macrophage-derived and lymphocyte-derived activating factors, and the almost simultaneous activation of multiple cell surface receptors, signaling pathways and transcription factors that ultimately all contribute to lymphocyte activation.
Evidence, including the marked expansion of macrophage numbers in smokers' lungs and in studies from genetically altered mice, also supports a role for macrophage-derived proteases in emphysema [ 16, 17].
The molecules responsible for the contribution by the soluble macrophage-derived LAFs still remain obscure, even today.