Words similar to macrophage-derived

Example sentences for: macrophage-derived

How can you use “macrophage-derived” in a sentence? Here are some example sentences to help you improve your vocabulary:

Accordingly, it is obvious that addition of a polyclonal activating ligand such as phytohemagglutinin to peripheral blood mononuclear cells (PBMCs) leads to the activation of soluble macrophage-derived and lymphocyte-derived activating factors, and the almost simultaneous activation of multiple cell surface receptors, signaling pathways and transcription factors that ultimately all contribute to lymphocyte activation.
Initially the nomenclature of IL-1 and IL-2 was created to delineate the sequential action of an assumed single macrophage-derived soluble factor (IL-1), which promoted the production of a single lymphocyte-derived factor (IL-2) [ 14 15 25 ] . However, the molecular nature of the LAF activity was never fully elucidated, even after the isolation and identification of multiple mitogen/endotoxin-stimulated macrophage-derived products, such as IL-1, IL-6, IL-12, IL-18, and Tumor Necrosis Factor-alpha (TNF-α).
The molecules responsible for the contribution by the soluble macrophage-derived LAFs still remain obscure, even today.
Evidence, including the marked expansion of macrophage numbers in smokers' lungs and in studies from genetically altered mice, also supports a role for macrophage-derived proteases in emphysema [ 16, 17].
It is probable that all of these macrophage-derived soluble factors together make up the activity originally ascribed to LAF.