Example sentences for: macrophage-like

How can you use “macrophage-like” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Precursor HL-60 cells are spherical and grow in suspension, whereas the differentiated macrophage-like cells become adherent and spread.

  • THP-1 cells were grown in RPMI 1640 media (GIBCO BRL) containing 10% fetal calf serum (FCS) (GIBCO BRL) at 37°C in 5% CO 2 [ 21 ] . To differentiate the THP-1 cells into macrophage-like cells, the cells were treated with 10 μM phorbol myristate acetate (PMA) (Sigma) as follows [ 21 ] . All PMA manipulations were done under low light conditions.

  • The tumor promoter phorbol myristate acetate (PMA) has been shown to activate the NADPH (nicotinamide adenine dinucleotide phosphate) oxidase and initiate the oxidative burst response in various phagocytes, including neutrophils and the macrophage-like cell line J774A.

  • For example, this agent is a potent inhibitor of microglia, the macrophage-like cells in the central nervous system [ 47 48 49 ] and shown to be effective in reducing the symptoms of experimental autoimmune encephalomyelitis (EAE), an animal model for the human disease multiple sclerosis [ 50 ] . Together, these results suggest that this agent may be useful in preventing ocular diseases that result from oxidative stress or inflammation.

  • After three passages, these primary cultures are depleted of macrophage-like type A synoviocytes [ S3 ] . Doubling time is stable between the third and the tenth passages, but marked reduction in proliferation rate occurs in later passage cells [ S4 ] .


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