Words similar to macrophage-like
Example sentences for: macrophage-like
How can you use “macrophage-like” in a sentence? Here are some example sentences to help you improve your vocabulary:
THP-1 cells were grown in RPMI 1640 media (GIBCO BRL) containing 10% fetal calf serum (FCS) (GIBCO BRL) at 37°C in 5% CO 2 [ 21 ] . To differentiate the THP-1 cells into macrophage-like cells, the cells were treated with 10 μM phorbol myristate acetate (PMA) (Sigma) as follows [ 21 ] . All PMA manipulations were done under low light conditions.
After three passages, these primary cultures are depleted of macrophage-like type A synoviocytes [ S3 ] . Doubling time is stable between the third and the tenth passages, but marked reduction in proliferation rate occurs in later passage cells [ S4 ] .
The normal intima of the synovium is one to two cells thick and consists mainly of macrophage-like and fibroblast-like cells [ 3 ] . In inflammation, macrophages make a large contribution to intimal thickening, where these cells increase in number and proportion [ 3 ] . Evidence indicates that intimal macrophages arrive via the circulation as monocytes [ 4 ] , and it is proposed that increased numbers of intimal macrophages in RA are largely attributed to enhanced monocyte recruitment from blood vessels in the synovium [ 1 5 ] . Neutrophils are also recruited in RA and can be found in abundance in synovial fluid, yet they occur in relatively low numbers in the synovium [ 5 ] . In synovial fluid their number can reach 10 6per joint, particularly during an active phase of the disease [ 6 ] . Neutrophils occur at the pannus-cartilage junction [ 7 ] and it is presumed that these cells reach the joint cavity by migrating from the blood vessels in the synovium, following a chemotactic gradient.
Using a novel indicator for oxidative activity, OxyBURST Green H 2 HFF BSA, I am able to study the distribution of lysosomal oxidative burst activity and its concurrent pH changes in live macrophage-like J744A.
Murine macrophage-like cell line (J774A.
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