Example sentences for: macrophage

How can you use “macrophage” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The culture was left at 37°C in 5% CO 2 for 2 hours, which resulted in the phagocytosis of about 10 bacteria per macrophage.

  • It is possible that macrophage activation is followed by release of pro-inflammatory chemokines such as IL-8, MCP-3, MIP-1α, MIP-β and MIG.

  • To evaluate the effects of IFN-γ on osteoclastogenesis, we utilized the mouse macrophage cell line RAW264.

  • The potency of IFN-γ as a macrophage activator and osteoclast inhibitor suggests a prominent role for T cells and/or NK cells in the regulation of bone resorption, as these cells constitute the major source of IFN-γ [ 18 ] . A link between activated T cells and osteoclast inhibition by IFN-γ has been highlighted in a report by Takayanagi et al ., providing the first in vivo evidence that the immune system may influence osteoclastogenesis [ 38 ] . Interestingly, other groups have demonstrated that activated T cells induce osteoclastogenesis via upregulation of surface RANKL, presenting a dilemma regarding the role of activated T cells in osteoclastogenesis [ 20 40 45 ] .

  • have previously monitored gene expression at various time points following phorbol ester-induced differentiation in the same HL-60 cell system [ 22 ] . Thirteen of the 22 transcripts we identified as cytoskeleton-associated were also assayed in that study by Tamayo, et al [ 22 ] . Only two of these transcripts-alpha spectrin and pim-1 were found to vary significantly, in that the expression of both genes was undetectable in the promyelocytic cell type and increased dramatically upon differentiation to the macrophage cell type.


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