Example sentences for: macrophage

How can you use “macrophage” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Subjection of the cells to a protocol leading to differentiation along the macrophage lineage led to a modest, time-dependent enhancement of resistin gene expression (Figure 1A).

  • LPS is a major component of the cell wall of gram-negative bacteria and is known to trigger a variety of inflammatory reactions in macrophages and other cells having CD14 receptors [ 7 8 ] . In particular, LPS is known to stimulate the macrophage secretion of nitric oxide [ 9 ] and inflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1-beta (IL-1-beta) [ 10 ] . For this reason, we also determined if TNF-alpha or IL-1-beta were capable of enhancing the cytotoxic effects of CEES.

  • CCL2, CCL3, CCL5 and CXCL8 occur in human RA synovial fluid and tissue [ 8 ] . Therefore the ligands for the binding sites described here occur endogenously within the RA joint, adding further evidence towards a role for these receptors in vivo . In the RA joint the synovial macrophage is among the principle cell types that produce CCL2, CCL3 and CXCL8 [ 8 17 ] . The finding of chemokine receptors on these cells suggests that macrophages may amplify inflammation by attracting cells of the same type, and other cell types, into the joint thereby setting up a positive feedback loop.

  • The murine macrophage cell line, J774.

  • Multiplicities of infection (moi) ranged between 2:1 and 30:1 (bacteria: macrophage ratio) in PBS.


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