Words similar to lxre
Example sentences for: lxre
How can you use “lxre” in a sentence? Here are some example sentences to help you improve your vocabulary:
LXRE LXR responsive elements
[ 34 ] found AA to be more potent than DHA (saturated and monounsaturated being ineffective) at inhibiting activation of SREBP-1c promoter and LXRE enhancer constructs, induced by co-expression of LXRα or -β.
One mechanism is to antagonize activation of the LXR receptor leading to fewer LXR/RXR heterodimer complexes to bind the LXRE in the SREBP-1c promoter and less SREBP-1c-mediated transcription of SRE-containing genes [ 34 ] . The PPARα signaling cascade intertwines with SREBP pathways since LC-PUFA also activate PPARα, which can induce LXRα expression [ 17 ] .
Within the SREBP promoter element, the liver X receptor (LXR)-responsive elements (LXRE) may have an important role [ 34 ] . LC-PUFA may affect SREBP-1c mediated transcription via several mechanisms.