Words similar to lrps
Example sentences for: lrps
How can you use “lrps” in a sentence? Here are some example sentences to help you improve your vocabulary:
These results are consistent with claims that LRPs can signal through an interaction of the carboxyterminus with Axin [ 13 ] .
Arrow, the fly homolog of the LRPs, which are thought to be Wnt co-receptors in mammalian cells, is an obvious candidate for such an interactive protein.
LRPs have been shown to bind to Wnt/Wg through the first and second EGF repeats of their extracellular domain [ 11 ] . Our unpublished work in mammalian cells and results from others [ 11 13 ] demonstrate that the expression of LRP6 or an aminoterminal truncation mutant (LRP6ΔN), which should no longer bind to Wnt, can activate the Wnt signaling pathway.
While the functions of Fz and Dsh remain to be clarified, it is possible that upon Wnt signaling, Fzs recruit Dsh to the membrane and Dsh brings Axin to the carboxyterminus of LRPs.
Since we have been unable to measure Arr or LRP proteins directly in transfected cells, we cannot distinguish between more efficient expression or greater inherent activity of the LRPs as an explanation of the different effects of LRPs and Arr.
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