Example sentences for: lrp

How can you use “lrp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Since we have been unable to measure Arr or LRP proteins directly in transfected cells, we cannot distinguish between more efficient expression or greater inherent activity of the LRPs as an explanation of the different effects of LRPs and Arr.

  • The observation that LRP5ΔN activates the Wnt/Wg signaling pathway in a Dsh-independent manner [ 14 ] , and our data with overexpressed LRP6ΔN and LRP6, further support this proposal.

  • We wished to ask whether Wnt/Wg can signal through LRP/Arrow in the absence of Fz.

  • Similar results were observed for full-length LRP6 (Figure 5B).

  • Mis-regulation of Wnt signaling leads to the development of several human cancers, including colon carcinomas and melanoma [ 1 ] . Canonical Wnt signaling initiates in the binding of a Wnt ligand to its cell surface receptor, members of the frizzled gene family, along with the co-receptor LRP5/6 [ 2 3 ] , leading to changes in the activities of cytoplasmic effectors resulting in the stabilization of beta-catenin protein.


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