Example sentences for: lrp

How can you use “lrp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • If the carboxyterminus of LRP6 can interact with Axin independently of DFz2 and Dsh, it might reduce the cytoplasmic level of Axin and help stabilize β-catenin.

  • We conclude that Wnt/Wg signaling requires functional interactions of both LRP/Arr and Fz classes of receptors, and the cytoplasmic component Dsh.

  • Furthermore, it was reported that LRP signaling can be activated in a Dsh - independent fashion [ 14 ] . These data suggest that Wnt/Wg could signal through LRP directly to the β-catenin destruction complex in a Fz- and Dsh-independent fashion.

  • We have also found that mammalian LRP6 can replace the need for Arr in this context (Figure 4) and that the aminoterminus of LRP6 must be maintained for most or all of the effect.

  • Consistent with this, it has been demonstrated that Dickkopf-1 inhibits Wnt/β-catenin signaling by binding to LRP5 or LRP6 to prevent Wnt-receptor complex formation [ 10 11 12 ] .


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