Words similar to lrp

Example sentences for: lrp

How can you use “lrp” in a sentence? Here are some example sentences to help you improve your vocabulary:

Therefore it is most likely that Wg, DFz2 and LRP/Arr form a trimeric ligand-receptor complex to activate the signaling pathway.
To investigate whether these constructs can also function in S2 cells and whether their activities can synergize with Wg, we transferred LRP6 and LRP6ΔN into the Drosophila expression vector pPacPL (Figure 4A) and tested them alone and with various combinations of Wg and DFz2 in S2 cells (Figure 4B).
Consistent with this, it has been demonstrated that Dickkopf-1 inhibits Wnt/β-catenin signaling by binding to LRP5 or LRP6 to prevent Wnt-receptor complex formation [ 10 11 12 ] .
In addition, LRP6 has been reported to bind Wnt-1 and to associate with Fz in a Wnt-dependent manner [ 8 ] . Taken together, these results support a co-receptor model: upon exposure to Wnts, LRP5 or LRP6 forms a complex with Wnt and Fzs, transducing the Wnt signal downstream to stabilize cytoplasmic β-catenin.
We conclude that Wnt/Wg signaling requires functional interactions of both LRP/Arr and Fz classes of receptors, and the cytoplasmic component Dsh.