Example sentences for: low-dose

How can you use “low-dose” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To incorporate potential heterogeneity in susceptibility into the virtual low-dose challenge experiments, we replaced the probability of success in the Bernoulli trials (see above) with the individual infection probabilities.

  • The statistical power achieved with the repeated low-dose challenge design is generally higher than that achieved with the single low-dose challenge design.

  • To maximize their epidemiological relevance, low-dose challenge experiments should therefore involve challenge doses that reflect transmission probabilities at the upper end of the spectrum.

  • To study how potential heterogeneity in susceptibility affected the power of low-dose challenge trials, we simulated experiments in which each animal was assigned an individual infection probability (see Methods).

  • In conclusion, the repeated low-dose challenge approach may enable us to assess the potential efficacy of vaccines and prophylactic treatment strategies more realistically, and more sensitively than the standard high-dose challenge approach.


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