Example sentences for: low-density

How can you use “low-density” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • ApoAIV protein is an anti-atherogenic component of high-density lipoprotein (HDL) particles and is also found in very low-density lipoproteins and chylomicrons [ 75 ] . It is involved in cholesterol absorption; low-density lipoprotein (LDL) clearance as a cofactor for hepatic lipase; increasing dolichol acylation; and increasing PE, but not PC, hydrolysis.

  • One straightforward explanation for the vulnerability of low-density cultures treated with H 2 O 2 is that more molecules of H 2 O 2 per cell were present in these low-density cultures, which caused a lower viability.

  • The WHR, a measure of central adiposity, is gaining increased use as a measure of etiologically significant obesity and is thought to be more closely related to pathology, especially coronary heart disease, diabetes mellitus and stroke [ 7 ] . The metabolic changes that accompany obesity include peripheral hyperinsulinemia, hyperglycemia and glucose intolerance, hypertriglyceridemia, decreased serum low-density lipoprotein, increased serum very low-density lipoprotein, increased serum leptin, dyslipidemia, increased serum cortisol clearance, increased serum C-peptide level, downregulation of insulin receptors and an exaggerated insulin response to an oral glucose load [ 12 13 14 15 ] . These changes, especially when they occur in early adulthood, may be of fundamental importance in the development of breast cancer [ 9 16 ] .

  • As indicated by their names, lipoprotein lipase (LPL) and low-density lipoprotein receptor (LDLR) genes are involved in lipid and cholesterol metabolism and were logically associated by literature profiling (Figure 6a).

  • It is generally accepted that the hydroxy acid form of statins are potent inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an enzyme that plays a critical role in cholesterol metabolism, where they block substrate accessibility to HMG-CoA reductase, effectively subverting cholesterol levels of HDL [ 19 20 21 ] . In addition to lowering cholesterol, statins seem to have a number of additional effects, such as the nitric oxide-mediated promotion of new blood vessel growth [ 22 ] , protection against oxidative modification of low-density lipoprotein, as well as anti-inflammatory effects and a reduction in C-reactive protein levels [ 23 ] . All statins limit cholesterol biosynthesis by inhibiting the committed step in the biosynthesis of isoprenoids and sterols [ 24 ] .


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