Words similar to low-density
Example sentences for: low-density
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ApoAIV protein is an anti-atherogenic component of high-density lipoprotein (HDL) particles and is also found in very low-density lipoproteins and chylomicrons [ 75 ] . It is involved in cholesterol absorption; low-density lipoprotein (LDL) clearance as a cofactor for hepatic lipase; increasing dolichol acylation; and increasing PE, but not PC, hydrolysis.
One straightforward explanation for the vulnerability of low-density cultures treated with H 2 O 2 is that more molecules of H 2 O 2 per cell were present in these low-density cultures, which caused a lower viability.
The WHR, a measure of central adiposity, is gaining increased use as a measure of etiologically significant obesity and is thought to be more closely related to pathology, especially coronary heart disease, diabetes mellitus and stroke [ 7 ] . The metabolic changes that accompany obesity include peripheral hyperinsulinemia, hyperglycemia and glucose intolerance, hypertriglyceridemia, decreased serum low-density lipoprotein, increased serum very low-density lipoprotein, increased serum leptin, dyslipidemia, increased serum cortisol clearance, increased serum C-peptide level, downregulation of insulin receptors and an exaggerated insulin response to an oral glucose load [ 12 13 14 15 ] . These changes, especially when they occur in early adulthood, may be of fundamental importance in the development of breast cancer [ 9 16 ] .
As indicated by their names, lipoprotein lipase (LPL) and low-density lipoprotein receptor (LDLR) genes are involved in lipid and cholesterol metabolism and were logically associated by literature profiling (Figure 6a).
It is generally accepted that the hydroxy acid form of statins are potent inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an enzyme that plays a critical role in cholesterol metabolism, where they block substrate accessibility to HMG-CoA reductase, effectively subverting cholesterol levels of HDL [ 19 20 21 ] . In addition to lowering cholesterol, statins seem to have a number of additional effects, such as the nitric oxide-mediated promotion of new blood vessel growth [ 22 ] , protection against oxidative modification of low-density lipoprotein, as well as anti-inflammatory effects and a reduction in C-reactive protein levels [ 23 ] . All statins limit cholesterol biosynthesis by inhibiting the committed step in the biosynthesis of isoprenoids and sterols [ 24 ] .