Words similar to low-density
Example sentences for: low-density
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Conflicting results have been reported from studies on the stroke risk factor status of genes related to myocardial infarction or arterial disease, such as specific genotypes of the genes for angiotensin 1-converting enzyme ( ACE ) [ 23 24 25 26 ] or apolipoprotein [ 27 28 29 30 31 32 33 34 ] . Potential confounding factors include the effects of comorbidity and differential mortality rates [ 34 35 ] . Although the degree of stenosis of the cervical internal carotid arteries in symptomatic patients correlates with risk of ipsilateral stroke [ 36 ] , no clear conclusions can be drawn from attempts to relate carotid artery disease to specific genotypes (for example, of the paraoxonase gene PON, which is thought to protect low-density lipoprotein against oxidative modification [ 37 ] , or of the endothelial nitric oxide synthase gene [ 38 ] ).
The blood lipid variables investigated were triglyceride (TRG), total cholesterol (TC), high-density lipoprotein (HDL) cholesterol concentrations, low-density lipoproteins (LDL) cholesterol concentrations and the ratio of total:HDL cholesterol (T:HDLC) [ 38 ] . All biochemical measurements were performed in an accredited hospital laboratory.
ApoAIV protein is an anti-atherogenic component of high-density lipoprotein (HDL) particles and is also found in very low-density lipoproteins and chylomicrons [ 75 ] . It is involved in cholesterol absorption; low-density lipoprotein (LDL) clearance as a cofactor for hepatic lipase; increasing dolichol acylation; and increasing PE, but not PC, hydrolysis.
Additionally, C-reactive protein reduces endothelial nitric oxide synthase, upregulates the proatherosclerotic NF-κB pathway, enhances low-density lipoprotein (LDL) uptake by macrophages, which become foam cells, and facilitates T-cell- and complement-mediated destruction and apoptosis of the endothelium [2,26,29–31].
Low-density mononuclear cells grown for 1 week in tissue culture with fetal calf serum (FCS) become adherent fibroblast-like cells and a few were large, flat, round cells.
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