Words similar to lipophilic

Example sentences for: lipophilic

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Because steroids are small lipophilic molecules that penetrate all tissues and are quickly metabolized and cleared, they appear to be ideal inducers for developing gene regulation systems that fulfill these criteria.
We hypothesize that it is unlikely that some members of the TMC family display an atypical topology, thus we propose that the lipophilic intracellular loop between TM6 and TM7 bears some flexibility, which may enable this domain to integrate into the inner surface of the phospholipid bilayer or even to pass through the plasmamembrane (Figure 2).
The Hh protein used in the studies described here was bacterially overexpressed amino-terminal human Shh modified at its amino-terminal cysteine by an octyl maleimide moiety [ 21 ] . This lipophilic Shh form showed comparable potency to native Shh in the cell-based reporter assay (data not shown).
Recent studies have expanded on this model to include another lipophilic region and a second hydrogen bonding interaction two atoms away from the first [ 19 20 21 ] . A compound that contains all five pharmacophoric regions was synthesized by Orjales et al [ 22 ] . This compound (1-(phenylmethyl)-2-piperizinyl benzimidazole or lerisetron) is shown in figure 1and is a potent 5-HT 3 R antagonist.
There are at least 17 cytochrome p450 gene families (Cyps), with four hepatic types (Cyps 1-4) that metabolize foreign compounds and lipophilic substrates, including hormones, FAs, drugs and xenobiotics.