Words similar to lif
Example sentences for: lif
How can you use “lif” in a sentence? Here are some example sentences to help you improve your vocabulary:
JM-1 ES cells [ 22] were expanded by culturing on feeder cells in medium supplemented with LIF.
Cells were plated on thirteen 10 cm 2tissue culture dishes and grown for two days in ES cell medium supplemented with LIF.
Basal POMC is reduced, but inducible upon stress [ 16 ] . Thus, an obligatory function of LIF may be in the processing of POMC to ACTH during acute stress.
Excess GC activity due to LIFR loss is an unexpected result since LIF gain-of-function mice develop a Cushing's-like syndrome [ 29 30 ] . Thus, if the relationship were simple, loss of LIFR function would predict development of GC insufficiency.
LIF and LIFR are functionally expressed in rodent tissues that are central to GC production: the hypothalamus [ 8 ] and pituitary [ 9 10 11 12 ] . LIF works in synergy with corticotropin-releasing hormone (CRH) in the hypothalamus to increase pituitary pro-opiomelanocortin (POMC) and, ultimately, pituitary adrenocorticotrophin hormone (ACTH) [ 9 11 13 14 15 16 ] . LIF also stimulates POMC gene expression directly in the pituitary [ 9 11 15 17 ] . LIF up-regulates pituitary prohormone convertase (PC1).