Example sentences for: lg

How can you use “lg” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • CYP2B6 expression was increased by TCPOBOP, as expected, and this response was blocked by LG1069 treatment.

  • To test whether the apparent allosteric effects of LG1069 on CAR transactivation vary with different response elements, the effect of the rexinoid on transactivation directed by cytochrome P450 response elements was examined.

  • For example, it is possible that the inhibitory effect of LG1069 in the stable CAR expressing cell line is based on the sequestration of limiting amounts of RXR into ligand-dependent homodimers, as has been suggested in previous studies using primary hepatocytes [ 17 ] . However, similar effects were observed with the relatively large amounts of RXR used for the biochemical studies or with the transient transfections, which relied on cotransfected RXR.

  • Finally, expression of the endogenous CYP2B6 gene in CAR expressing HepG2 cells is modestly inhibited by LG1069 alone, androstanol alone and the combination of both.

  • Similar results were observed with the tandem DR-4 sites from the CYP2B10 gene, except that LG1069 did not have a significant stimulatory effect on its own, but did augment the effect of TCPOBOP.


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