Example sentences for: lg

How can you use “lg” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To examine the effects of RXR ligands on CAR transactivation in a more functional context, the rexinoid LG1069 was combined with the CAR inverse agonist androstanol and the agonist TCPOBOP in a series of transient transfection studies using different response elements.

  • In contrast to the results with the DR-5 site, but in agreement with the biochemical results, LG1069 alone had a stimulatory effect on the ER-6 CAR response element from the promoter of the CYP3A4 gene (Fig.

  • In more detailed dose response studies, 100 nM LG1069 decreased the inhibitory effect of androstanol by as much as 70% and had an even stronger effect on TCPOBOP activation (Fig.

  • In contrast to the results with the transient transfections with the CYP response elements, CYP2B6 expression was decreased to a comparable extent by androstanol, LG1069, and the combination of both ligands.

  • On the tandem CYP2B10 elements, LG1069 does not have a stimulatory effect on its own and does not decrease the inhibitory effect of androstanol, but it does increase response to TCPOBOP.


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