Words similar to lcr

Example sentences for: lcr

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This plasmid, called pCD1 [ 1 ] in Y. pestis , encodes for a type III secretion apparatus necessary for the translocation of effector proteins (Yops) into eukaryotic target cells [ 2 ] . The net result of this polarized toxin translocation is the disruption of eukaryotic cell signalling and structure [ 2 ] . Induction of the virulence-related genes on pCD1 is linked to an in vitro phenomenon termed the Low Calcium Response (LCR).
The result of this in vitro induction of virulence genes is the massive secretion of Yops into the growth medium, accompanied by a characteristic growth restriction that is a hallmark phenotype of the LCR [ 3 ] .
For NAHR to have had a role, however, one must presume the presence of a GLP/LCR15-related sequence on the ancestral 15p.
Location of the insertion was not determined but the LCR phenotype and ability to translocate Yops into HeLa cells was verified (data not shown).
3 previously described by Riley et al . [ 17 ] , and several copies of a duplicon described as Golgin-linked-to-PML (GLP) [ 18 ] and as LCR15 [ 19 20 21 ] . A third, previously undetected, potential segmental duplication was identified in the proximal third of the 600 kb region (Figure 4, indicated by the asterisk).