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Example sentences for: lctx

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In addition, whereas only 27% of patients affected by bone metastases had α LCTX values below the mean of nonmetastasised controls (NC-patients), 52% of these patients had α L/α Dratios below this value (Fig.
The α LCTX isoform reflecting resorption of young bone appeared to provide the best differentiation of patients affected by breast cancer-induced bone metastases.
The levels of the three CTX isoforms α L, β Land α Dwere 2.3-fold to 2.7-fold higher in the postmenopausal women (Table 1), in accordance with previous reports of CTX levels during the menopause [ 15 ] . As all forms were elevated to the same magnitude in postmenopause, the ratios between the newly synthesised α LCTX form and the older β Land α DCTX forms was not significantly different in premenopausal and postmenopausal women.
HC+ patients had a 3.4-fold elevation in α LCTX levels, and a 2.2-fold elevation was seen in NC+ patients, indicating that the more severe condition in the HC+ patients is reflected by the α LCTX marker.
When individual Z scores of CTX were calculated for the metastatic breast cancer patients compared with the non-metastatic patients, the α LCTX form and the α L/α DCTX ratio showed the highest average increases in accordance with the ability of the α LCTX levels and the α L/α DCTX ratio to most sensitively reflect alterations in the balance between the anabolic and catabolic processes of bone turnover (Fig.